Dec 24, 2024 · ADH7 (Alcohol Dehydrogenase 7 (Class IV), Mu Or Sigma Polypeptide) is a Protein Coding gene. Diseases associated with ADH7 include Alcohol Dependence and Atrophic Gastritis. Among its related pathways are Oxidation by …

This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid …

Gene ID: 131, updated on 8-Feb-2025. This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products.

Title: Expression of retinoic acid signaling components ADH7 and ALDH1A1 is reduced in aniridia limbal epithelial cells and a siRNA primary cell based aniridia model. The results of the study do not support our hypothesis that ADH1B and ADH7 genotypes affect blood ethanol, and acetaldehyde concentration.

该基因编码 IV 类乙醇脱氢酶 7 μ 或 sigma 亚基，是乙醇脱氢酶家族的一员。 该家族的成员代谢多种底物，包括乙醇、视黄醇、其他脂肪醇、羟基类固醇和脂质过氧化产物。 该基因编码的酶在乙醇氧化中效率低下，但作为视黄醇脱氢酶最为活跃；因此它可能参与视黄酸的合成，视黄酸是一种对细胞分化很重要的激素。 该基因在胃中的表达比在肝脏中丰富得多，因此不同于其他已知的基因家族成员。 可变剪接导致多个转录本变体。 [RefSeq 提供，2009 年 10 月]

Dec 10, 2024 · This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products.

ADH is a zinc-containing enzyme that consists of two protein subunits (dimeric enzyme). ADH can oxidize endogenous ethanol produced by microorganisms in the gut as well as consumed ethanol. ADH has broad substrate specificity and can metabolize primary as well as secondary alcohol, such as methanol, propanol, and ethylene glycol.

这个基因编码IV类乙醇脱氢酶7μ或σ亚基，属于乙醇脱氢酶家族成员。 这个家族的成员代谢各种底物，包括乙醇、视黄醇、其他脂肪醇、羟基固醇和脂质过氧化产物。 这个基因编码的酶在乙醇氧化中效率低下，但作为视黄醇脱氢酶的活性最高；因此它可能参与视黄酸合成的过程，视黄酸是一种对细胞分化重要的激素。 这个基因在胃中的表达比肝脏丰富得多，这与已知的其他基因家族成员不同。 选择性剪接导致多个转录变异体。 [RefSeq，2009年10月提供] Dir./Indir. The status, …

Description: alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide (from HGNC ADH7) RefSeq Summary (NM_000673): This gene encodes class IV alcohol dehydrogenase 7 mu or sigma subunit, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other ...

Mar 3, 1995 · We have now analyzed genomic clones encoding the class IV ADH gene, which we refer to as ADH7. The intron/exon structure was determined, and the promoter region was identified. We also show that the class IV ADH gene, unlike other ADH genes, is expressed much higher in the stomach than in the liver.