ACSL4 - Wikipedia
Long-chain-fatty-acid—CoA ligase 4 is an enzyme that in humans is encoded by the ACSL4 gene. [5] [6] [7] The protein encoded by this gene is an isozyme of the long-chain fatty-acid …
ACSL4 Gene - GeneCards | ACSL4 Protein | ACSL4 Antibody
2024年12月24日 · ACSL4 (Acyl-CoA Synthetase Long Chain Family Member 4) is a Protein Coding gene. Diseases associated with ACSL4 include Intellectual Developmental Disorder, X …
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid ...
We applied two independent approaches-a genome-wide CRISPR-based genetic screen and microarray analysis of ferroptosis-resistant cell lines-to uncover acyl-CoA synthetase long …
ACSL4 as a Potential Target and Biomarker for Anticancer: From ...
2022年7月13日 · Recently, acyl-CoA synthetase long-chain family 4 (ACSL4) is found be participated in the activation of long chain fatty acids metabolism, immune signaling …
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid ...
2016年11月14日 · We applied two independent approaches—a genome-wide CRISPR-based genetic screen and microarray analysis of ferroptosis-resistant cell lines—to uncover acyl-CoA …
The ACSL4 Network Regulates Cell Death and Autophagy in …
ACSL4 is an enzyme that catalyzes the formation of long-chain acyl-CoA molecules, which are important intermediates in the biosynthesis of various types of lipids. ACSL4 is found in many …
ACSL4, PUFA, and ferroptosis: new arsenal in anti-tumor immunity …
2022年4月22日 · IFNγ secreted by CD8 + T cells binds to IFNR, activates the JAK-STAT1-IRF1 signaling axis, and induces ACSL4 expression in tumor cells. The increase in ACSL4 …
Acyl-CoA synthase ACSL4: an essential target in ferroptosis and …
ACSL4 remodels the phospholipid composition of cell membranes, regulates steroidogenesis, and balances eicosanoid biosynthesis. In addition, ACSL4-mediated metabolic reprogramming and …
ACSL4 acyl-CoA synthetase long chain family member 4 [ (human)]
ACSL4 reprograms fatty acid metabolism in hepatocellular carcinoma via c-Myc/SREBP1 pathway. New inhibitor targeting Acyl-CoA synthetase 4 reduces breast and prostate tumor …
ACSL4 acyl-CoA synthetase long chain family member 4
2025年2月9日 · Clinical resource with information about ACSL4, Intellectual disability, X-linked 63, and available tests. There are links to practice guidelines and authoritative resources like …