2024年12月24日 · ANK3 (Ankyrin 3) is a Protein Coding gene. Diseases associated with ANK3 include Intellectual Developmental Disorder, Autosomal Recessive 37 and Ank3-Related Intellectual Disability-Sleep Disturbance Syndrome. Among its related pathways are Transport to the Golgi and subsequent modification and Nervous system development.

The protein encoded by the ANK3 gene is a member of the ankyrin family of proteins that link the integral membrane proteins to the underlying spectrin-actin cytoskeleton. Ankyrins play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains.

2025年2月9日 · Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

2022年7月6日 · Ankyrin proteins act as molecular scaffolds and play an essential role in regulating cellular functions. Recent evidence has implicated the ANK3 gene, encoding ankyrin-G, in bipolar disorder...

ANK3 encodes multiple isoforms of ankyrin-G, resulting in variegated tissue expression and function, especially regarding its role in neuronal development. Based on the zygosity, location, and type, ANK3 variants result in different neurodevelopmental phenotypes.

2025年1月4日 · Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]

锚蛋白 3 是一种免疫学上不同于锚蛋白 1 和 2 的基因产物，最初发现于中枢和周围神经系统中神经元的轴突起始段和朗飞叶节点。 已发现该基因编码不同异构体的多个转录变体。 [RefSeq 提供，2011 年 2 月]

Ank3（上皮锚蛋白）是锚蛋白基因家族和肾脏中主要锚蛋白的一种广泛分布的新成员，以交替剪接的形式表达，包括缺少重复结构域的形式。 ,Journal of Cell Biology - X-MOL. Ank3（上皮锚蛋白）是锚蛋白基因家族和肾脏中主要锚蛋白的一种广泛分布的新成员，以交替剪接的形式表达，包括缺少重复结构域的形式。 Division of Hematology/Oncology, Children's Hospital, Boston, Massachusetts 02115, USA. 我们从小鼠肾脏cDNA克隆了一种新型锚蛋白Ank3。 预测全长转 …

Ankyrin 3 is an immunologically distinct gene product from ankyrins 1 and 2, and was originally found at the axonal initial segment and nodes of Ranvier of neurons in the central and peripheral nervous systems. p.? p.Met1?

2025年2月9日 · ANK3 expression is associated with androgen receptor stability, invasiveness, and lethal outcome in prostate cancer patients. Nonsense mutation in ANK3 was identified in a patient with speech impairment, intellectual disability and autistic features.