The suspect human hepatocarcinogen aflatoxin B1 (AFB1) is a well-known potent initiator of hepatic tumors in rainbow trout (Oncorhynchus mykiss). Both hepatocellular carcinomas and …

Aflatoxin B1 (AFB1) is a fungal metabolite found in animal feeds and human foods. It is one of the most toxic and carcinogenic of aflatoxins and is classified as a Group 1 carcinogen. Dietary …

2023年2月19日 · AFB1 is believed to be the most potent among all aflatoxins. Aflatoxin M1 (AFM1) is found in the fermentation broth of A. parasiticus, but it and aflatoxin M2 are also …

In the case of aflatoxin B1 (AFB1), the best studied aflatoxin, AFB1-exo 8,9-epoxide, which is formed as the first step of AFB1 metabolism by microsomal cytochrome enzyme (CYP450) …

This review focuses on the metabolism of AFB1, including epoxidation and DNA adduction, as it concerns the initiation of cancer and the underlying mechanisms. In addition to DNA …

2019年2月1日 · Aflatoxin B1 (AFB1) is the most potent of these compounds and has been well-characterized to lead to the development of hepatocellular carcinoma (HCC) in humans and …

Aflatoxin B1 (AFB1) has been reported to synergize with hepatitis B virus (HBV) to induce development of hepatocellular carcinoma (HCC).

Aflatoxins are fungal metabolites found in feeds and foods. When the ruminants eat feedstuffs containing Aflatoxin B1 (AFB1), this toxin is metabolized and Aflatoxin M1 (AFM1) is excreted …

Aflatoxins (AFs) represent one of the main mycotoxins produced by Aspergillus flavus and Aspergillus parasiticus, with the most prevalent and lethal subtypes being AFB1, AFB2, AFG1, …

2022年5月1日 · Aflatoxins B 1 (AFB 1) is a hepatoxic compound produced by Aspergillus flavus and Aspergillus parasiticus, seriously threatening food safety and the health of humans and …

2024年10月17日 · Aflatoxin B1 (AFB1) is a fungal toxin consistently found as a contaminant in food products such as cereals, nuts, spices, and oilseeds. AFB1 exposure can lead to …

2024年11月11日 · Aflatoxin B1 (AFB1) is a mycotoxin that widely found in the environment and mouldy foods. AFB1 initially targets the intestine, and AFB1-induced intestinal injury cannot be …

This review focuses on the metabolism of AFB1, including epoxidation and DNA adduction, as it concerns the initiation of cancer and the underlying mechanisms. The link between AFB1 …

Aflatoxin B1 (AFB1) exhibits the most potent mutagenic and carcinogenic activity among aflatoxins. For this reason, AFB1 is recognized as a human group 1 carcinogen by the …

4 天之前 · Accurate and rapid aflatoxin B1 (AFB1) detection is essential for ensuring the safety of food supplies. In this paper, we introduce a distance-readout paper-based microfluidic chip …

Aflatoxins B 1 (AFB 1) is a hepatoxic compound produced by Aspergillus flavus and Aspergillus parasiticus, seriously threatening food safety and the health of humans and animals. …

AFB1 is the most carcinogenic of AF. AFB1 contamination of agricultural commodities poses a considerable risk to human and livestock health and high economic losses occur in the country …

The International Agency for Research on Cancer classified AFB1 as a group 1 human carcinogen in 1993, based on sufficient evidence in humans and experimental animals and it …

From an epidemiological point of view, AFB1 is the most hepatocarcinogenic agent and a main contributor to the high rate of HCC. AFB1 is considered to be an unavoidable contaminant of …

2021年8月9日 · Here, we carried out a genome-wide CRISPR-Cas9 genetic screen to identify aflatoxin B1 (AFB1) targets. Among the most significant hits was the aryl hydrocarbon receptor …