ABCB4 - Wikipedia
The ATP-binding cassette 4 (ABCB4) gene encodes multidrug resistance protein 3. [5] [6] [7] ABCB4 is associated with progressive familial intrahepatic cholestasis type 3 and intrahepatic …
ABCB4 Gene - GeneCards | MDR3 Protein | MDR3 Antibody
Dec 24, 2024 · ABCB4 (ATP Binding Cassette Subfamily B Member 4) is a Protein Coding gene. Diseases associated with ABCB4 include Cholestasis, Progressive Familial Intrahepatic, 3 and …
ABCB4基因的研究进展.doc 6页 VIP - 原创力文档
Jul 10, 2017 · ABCB4基因编码的蛋白是一种磷脂酰胆碱易位酶，可以将磷脂酰胆碱转移人胆汁 ，乳化胆汁中的胆盐，保护胆管上皮免受胆盐损伤[1] 。 ABCB4基因的突变可能会导致胆管损 …
ABCB4 disease: Many faces of one gene deficiency
Mar 1, 2020 · ATP-binding cassette (ABC) subfamily B member 4 (ABCB4), also known as multidrug resistance protein 3 (MDR3), encoded by ABCB4, is involved in biliary phospholipid …
汤善宏教授团队：胆汁酸代谢过程中转运蛋白基因突变机制及临床 …
Mar 11, 2023 · MDR3由ABCB4编码，主要在肝细胞的小管膜上表达并充当磷脂转运蛋白。 它的功能主要是将肝细胞内的磷脂酰胆碱转运到胆管腔，与胆汁酸混合后降低对胆管细胞毒性作用。 …
ABCB4 gene - MedlinePlus
The ABCB4 gene (also known as MDR3) provides instructions for making a protein that helps move certain fats called phospholipids across the membranes of liver cells. The protein …
Structure of the human lipid exporter ABCB4 in a lipid environment
Dec 23, 2019 · ABCB4 is an ATP-binding cassette transporter that extrudes phosphatidylcholine into the bile canaliculi of the liver. Its dysfunction or inhibition by drugs can cause severe, …
ATP 结合盒亚家族 B 成员 4（ABCB4）基因 | MCE
关于 abcb4 Cytogenetic location: 7q21.12 Genomic coordinates (GRCh38): 7:87,365,896-87,476,027 (from NCBI) This gene has 12 transcripts (splice variants), 189 orthologues, 10 …
ABCB4突变基因型与表型的相关性 - lcgdbzz.org
Abstract: ABCB4-related disease is the syndrome of bile secretion disorder caused by gene mutations and can cause bile duct injury, portal hypertension, and liver cirrhosis in clinical …
ATP结合盒亚家族B成员4（ABCB4）基因突变相关性肝硬化合并胆 …
ATP结合盒亚家族B成员4（ABCB4）基因突变疾病谱涉及进行性家族性肝内胆汁淤积3型、胆石症、妊娠期肝内胆汁淤积症、门静脉高压、肝硬化，甚至原发性肝脏、胆道恶性肿瘤等多种疾病 …