
snRNP - Wikipedia
snRNPs (pronounced "snurps"), or small nuclear ribonucleoproteins, are RNA-protein complexes that combine with unmodified pre-mRNA and various other proteins to form a spliceosome, a …
核小核糖核蛋白 - 维基百科,自由的百科全书
核小核糖核蛋白(英文:small nuclear ribonucleoproteins,簡稱snRNP)是一種大型RNA-蛋白質複合物,其與未修飾的mRNA前體(pre-mRNA)和各種其他蛋白質結合形成剪接體,功能 …
核微小核糖核蛋白颗粒 - 百度百科
核微小核糖核蛋白颗粒(small nuclear ribonucleoprotein particles,snRNP),又称剪接体、小分子核糖核蛋白,参与真核生物DNA的转录过程。
Structure of the human 20S U5 snRNP
2024年3月11日 · The 20S U5 small nuclear ribonucleoprotein particle (snRNP) is a 17-subunit RNA–protein complex and a precursor of the U4/U6.U5 tri-snRNP, the major...
Nature | U1 snRNP调控非编码RNA结合染色质的新机制 - 知乎
上世纪80年代初,Joan Steitz通过系统性红斑狼疮患者血液抗体分离提取 U1、U2、U4、U5和U6小核糖核蛋白粒子(又称为 snRNP),揭示了它们参与RNA剪接的经典功能【4,5】。近年来 …
Molecular architecture of the human 17S U2 snRNP | Nature
2020年6月3日 · The cryo-EM structure of human U2 small nuclear ribonucleoprotein (snRNP) offers insights into what rearrangements are required for this snRNP to be stably incorporated …
SnRNP - an overview | ScienceDirect Topics
SnRNP, or small nuclear ribonucleoprotein, is a class of RNAs that, after assembly with specific proteins, form the core of the spliceosome. The spliceosome is responsible for removing …
西湖大学施一公团队揭示剪接体进行分支位点选择、校正的分子机理
2024年1月9日 · 剪接体是一个巨大且高度动态的分子机器,其核心组成元件为5种核内小核糖核蛋白复合物(snRNP),分别为U1,U2,U4,U5和U6 snRNP。 剪接体通过识别pre-mRNA上 …
The assembly of a spliceosomal small nuclear ribonucleoprotein …
Remarkably, the penta-snRNP forms in absence of pre-mRNA, thus, distinguishing it from a spliceosome. In addition, the penta-snRNP was shown to splice RNA substrates upon …
snRNP Proteins - SpringerLink
An snRNP protein which recognizes the polypyrimidine tract at the 3’ end of an intron and a second protein of molecular weight 25,000 are candidates for U5 specific polypeptides. Two …
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