miR-21: a non‐specific biomarker of all maladies
2021年3月12日 · miR-21 is clearly involved in key regulatory pathways. Modulating its expression in in vivo and in vitro studies show clear and important phenotype changes. We may ultimately …
mIRN21 - Wikipedia
miR-21 is one of the most frequently upregulated miRNAs in solid tumours, and its high levels were first described in B cell lymphomas. Overall, miR-21 is considered to be a typical 'onco …
miR-RNA在癌症领域的研究~（前沿篇） - 知乎专栏
1.miRNA简写成miR-No,如miR-21. 2.高度同源的miRNA在No.其后加英文字母，如miR-199a和miR-199b. 3.由于不同染色体上的DNA序列转录加工而成的具有相同成熟序列的miRNA，则在后面加 …
Regulation and function of miRNA-21 in health and disease
The small regulatory RNA microRNA-21 (miR-21) plays a crucial role in a plethora of biological functions and diseases including development, cancer, cardiovascular diseases and …
MicroRNA⁃21（miR⁃21） 是人类细胞中早期发现的miRNAs之一，在多种癌症中处于明显高表达状态，其异常表达与癌症的 发生发展密切相关。该文对miR⁃21在恶性肿瘤发生发展、转移、治 …
miR-21: a small multi-faceted RNA - PubMed
In this review, we summarise the current knowledge of miR-21 functions in human disease, with an emphasis on its regulation, oncogenic role, targets in human cancers, potential as a …
The Promising Role of miR-21 as a Cancer Biomarker and Its Importance ...
2020年6月5日 · miR-21 has demonstrated its potential as a diagnostic biomarker for different types of cancer, such as breast, colorectal, and pancreatic cancers. In particular, Iorio et al. 56 …
MicroRNA-21 is immunosuppressive and pro-metastatic via
2022年7月11日 · Since miR-21 is recognised as being associated with poor prognosis in cancer, we investigated its contribution to mammary tumour growth and metastasis in tumours with …
MIR21 microRNA 21 [Homo sapiens (human)] - Gene - NCBI
2025年2月19日 · Title: miR-21 Exerts Anti-proliferative and Pro-apoptotic Effects in LPS-induced WI-38 Cells via Directly Targeting TIMP3. A miRNA-21-Mediated PTEN/Akt/NF-kappaB Axis …
miR-21，一种用于癌症治疗的致癌靶标miRNA：化学 ... - X-MOL
microRNA-21（miR-21）在几乎所有类型的癌症中均具有潜在的致癌功能，并靶向肿瘤抑制蛋白。 已就细胞增殖，迁移，侵袭，转移和凋亡调控研究了miR-21过表达。