Heterogeneous ribonucleoprotein particle （异构核糖核蛋白颗粒）是一类存在于细胞核中的RNA与蛋白复合体，其主要存在在基因转录和随后的新合成的RNA的转录后调控过程中，参与核酸代谢过程。 在RNA合成加工过程中，由于结合在pre-mRNA上的蛋白发出了“pre-mRNA还没有完成加工过程”这样的一个信号，因此未完成加工的pre-mRNA不能运输到细胞质。 在RNA合成加工完成后，成熟的RNA通常会被非常快的从细胞核中运输出去，因此大多数核内的RNA结合蛋白是 …

Heterogeneous nuclear ribonucleoproteins (hnRNPs) represent a large family of RNA-binding proteins (RBPs) that contribute to multiple aspects of nucleic acid metabolism including alternative splicing, mRNA stabilization, and transcriptional and translational regulation.

Heterogeneous nuclear ribonucleoproteins (hnRNPs) are complexes of RNA and protein present in the cell nucleus during gene transcription and subsequent post-transcriptional modification of the newly synthesized RNA (pre-mRNA).

May 23, 2016 · Heterogeneous nuclear ribonucleoproteins (hnRNPs) represent a large family of RNA-binding proteins (RBPs) that contribute to multiple aspects of nucleic acid metabolism including alternative splicing, mRNA stabilization, and transcriptional and translational regulation.

Aug 2, 2022 · 异质核核糖核蛋白（hnRNPs） 是高等真核生物中含量最丰富的核蛋白，是一类RNA结合蛋白。 HnRNPA/B亚家族是hnRNPs的核心成员，与癌症的发生和发展密切相关。 …

Sep 29, 2021 · 核不均一核糖核蛋白（heterogeneous nuclear ribonucleoprotein，hnRNP）是一类多功能RNA结合蛋白家族，能与RNA聚合酶Ⅱ合成的新生转录本结合，并以复合体形式参与转录本稳定与成熟调控过程. hnRNP A1是hnRNPs家族重要成员，不仅广泛参与癌症与神经系统疾病相关 …

Nov 24, 2023 · Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a family of RNA-binding proteins that bind to the primary transcripts of protein-coding genes. hnRNPs play a critical role in controlling the maturation, transport, and interaction of newly formed heterogeneous nuclear RNAs with other nuclear structures, which are essential for pre-mRNA proce...

Heterogeneous nuclear ribonucleoproteins (hnRNPs) comprise a family of RNA-binding proteins. The complexity and diversity associated with the hnRNPs render them multifunctional, involved not only in processing heterogeneous nuclear RNAs (hnRNAs) into mature mRNAs, but also acting as trans -factors in regulating gene expression.

Oct 4, 2024 · Heterogeneous nuclear ribonucleoproteins (HNRNPs) represent a large family of RNA-binding proteins consisting of more than 20 members and have attracted great...

Jan 8, 2024 · Herein, we establish that dysfunction of the RNA binding protein heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) results in differential of binding to RNA targets causing alternative RNA...