
YTHDF2 Gene - GeneCards | YTHD2 Protein | YTHD2 Antibody
2024年12月25日 · YTHDF2 (YTH N6-Methyladenosine RNA Binding Protein F2) is a Protein Coding gene. Diseases associated with YTHDF2 include Myeloid Leukemia and Ocular …
YTHDF2 destabilizes m6A-containing RNA through direct ... - Nature
2016年8月25日 · Here we report that m 6 A-containing RNAs exhibit accelerated deadenylation that is mediated by the CCR4–NOT deadenylase complex.
The biological function of m6A reader YTHDF2 and its role in …
2021年2月16日 · YT521-B homology domain family 2 (YTHDF2) is a member of m6A “readers” and its role in human diseases remains unclear. Accumulating evidence suggests that …
YTHDF2 promotes ATP synthesis and immune evasion in B cell …
2024年12月17日 · YTHDF2 modulates oncogenic transformation and immune evasion across multiple B cell cancers by stabilizing m5C-modified mRNAs and destabilizing m6A-modified …
YTHDF2 orchestrates tumor-associated macrophage …
2023年1月19日 · Here, we show that the N6 -methyladenosine reader YTHDF2 regulates the antitumor functions of TAMs. YTHDF2 deficiency in TAMs suppressed tumor growth by …
YTHDF2 reduction fuels inflammation and vascular ... - PubMed
2019年11月18日 · YTHDF2 silenced in human HCC cells or ablated in mouse hepatocytes provoked inflammation, vascular reconstruction and metastatic progression.
YTHDF2 inhibition potentiates radiotherapy antitumor efficacy
2023年7月10日 · Pharmacological inhibition of YTHDF2 overcomes MDSC-induced immunosuppression and improves combined IR and/or anti-PD-L1 treatment. Thus, YTHDF2 …
YTHDF2 facilitates aggresome formation via UPF1 in an m
2023年10月6日 · YTHDF2 has been extensively studied and typified as an RNA-binding protein that specifically recognizes and destabilizes RNAs harboring N6 -methyladenosine (m 6 A), …
YTHDF2 inhibition potentiates radiotherapy antitumor efficacy
2023年5月25日 · Following IR, loss of Ythdf2 in myeloid cells augments antitumor immunity and overcomes tumor radioresistance by altering MDSC differentiation and inhibiting MDSC …
YTHDF2 YTH N6-methyladenosine RNA binding protein F2
2025年2月9日 · YTHDF2 Binds to 5-Methylcytosine in RNA and Modulates the Maturation of Ribosomal RNA. YTHDF2 promotes the liver cancer stem cell phenotype and cancer …
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