2024年12月25日 · YTHDF2 (YTH N6-Methyladenosine RNA Binding Protein F2) is a Protein Coding gene. Diseases associated with YTHDF2 include Myeloid Leukemia and Ocular …

2016年8月25日 · Here we report that m 6 A-containing RNAs exhibit accelerated deadenylation that is mediated by the CCR4–NOT deadenylase complex.

2021年2月16日 · YT521-B homology domain family 2 (YTHDF2) is a member of m6A “readers” and its role in human diseases remains unclear. Accumulating evidence suggests that …

2024年12月17日 · YTHDF2 modulates oncogenic transformation and immune evasion across multiple B cell cancers by stabilizing m5C-modified mRNAs and destabilizing m6A-modified …

2023年1月19日 · Here, we show that the N6 -methyladenosine reader YTHDF2 regulates the antitumor functions of TAMs. YTHDF2 deficiency in TAMs suppressed tumor growth by …

2019年11月18日 · YTHDF2 silenced in human HCC cells or ablated in mouse hepatocytes provoked inflammation, vascular reconstruction and metastatic progression.

2023年7月10日 · Pharmacological inhibition of YTHDF2 overcomes MDSC-induced immunosuppression and improves combined IR and/or anti-PD-L1 treatment. Thus, YTHDF2 …

2023年10月6日 · YTHDF2 has been extensively studied and typified as an RNA-binding protein that specifically recognizes and destabilizes RNAs harboring N6 -methyladenosine (m 6 A), …

2023年5月25日 · Following IR, loss of Ythdf2 in myeloid cells augments antitumor immunity and overcomes tumor radioresistance by altering MDSC differentiation and inhibiting MDSC …

2025年2月9日 · YTHDF2 Binds to 5-Methylcytosine in RNA and Modulates the Maturation of Ribosomal RNA. YTHDF2 promotes the liver cancer stem cell phenotype and cancer …