XPhos is a phosphine ligand derived from biphenyl. Its palladium complexes exhibit high activity for Buchwald-Hartwig amination reactions involving aryl chlorides and aryl tosylates. Both palladium and copper complexes of the compound exhibit high activity for the coupling of aryl halides and aryl tosylates with various amides . [ 1 ]

XPhos [2-Dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl] is an air-stable electron-rich biaryl monophosphine ligand 2 developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions.

2-Dicyclohexylphosphino-2',4',6'-triisoprophylbiphenyl | C33H49P | CID 11155794 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

2025年1月27日 · Exceptional ligands for Pd-catalyzed amination and amidation of aryl sulfonates. XPHOS is used as a regent in the synthesis of novel [1,2,4]triazolo[4,3-a]pyrazine derivatives as potential selective c-met inhibitors with improved pharmacokinetic properties. Uses. suzuki reaction. General Description. This product has been enhanced for catalytic ...

Dialkylbiaryl phosphine ligands are phosphine ligands that are used in homogeneous catalysis. They have proved useful in Buchwald-Hartwig amination and etherification reactions as well as Negishi cross-coupling, Suzuki-Miyaura cross-coupling, and related reactions. [1] .

Phos Pd G3 is the general formula for the complexes 3 and 5 (for 3 Phos = Xphos, for 5 Phos = RuPhos). See text for details. Catalyst quality plays an important role in the success of the catalytic transformations.

XPhos (2-(Dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. - Mechanism of Action & Protocol.