Protein Wnt-5a - Wikipedia
Protein Wnt-5a is a protein that in humans is encoded by the WNT5A gene. [5][6] The WNT gene family consists of structurally related genes that encode secreted signaling lipid modified …
WNT5A Gene - GeneCards | WNT5A Protein | WNT5A Antibody
2024年12月25日 · WNT5A (Wnt Family Member 5A) is a Protein Coding gene. Diseases associated with WNT5A include Robinow Syndrome, Autosomal Dominant 1 and Autosomal …
WNT-5A: signaling and functions in health and disease - PMC
WNT-5A, a prototypical WNT of β-catenin-independent branch, is highly conserved among species and plays key roles in the processes governing embryonic development, post-natal …
Wnt5a: its signalling, functions and implication in diseases
Wnt5a is a representative ligand that activates the β-catenin-independent pathways. Because the β-catenin-independent pathway includes multiple signalling cascades in addition to the planar …
WNT5A Wnt family member 5A [ (human)] - National Center for ...
WNT5A is a putative epi-driver of prostate cancer metastasis to the bone. Differential expression of WNT5A long and short isoforms in non-muscle-invasive bladder urothelial carcinoma. …
WNT5A gene - MedlinePlus
The WNT5A gene is part of a large family of WNT genes, which play critical roles in development starting before birth. Learn about this gene and related health conditions.
WNT5A Wnt family member 5A [ Homo sapiens (human) ]
2025年2月8日 · Title: WNT5A regulates the proliferation, apoptosis and stemness of human stem Leydig cells via the β-catenin signaling pathway. Exploring the role of the WNT5A rs566926 …
Wnt5a Signaling in Normal and Cancer Stem Cells - PMC
Wnt5a signaling is critical for regulating normal developmental processes, including stem cell self-renewal, proliferation, differentiation, migration, adhesion, and polarity.
Wnt5a and its signaling pathway in angiogenesis - PubMed
Wnt5a, a secreted glycoprotein, belongs to the noncanonical Wnt family involved in a wide range of organism development and tissue homeostasis. Wnt5a and its signaling pathway can …
WNT5A Wnt family member 5A - NIH Genetic Testing Registry …
Clinical resource with information about WNT5A, Autosomal dominant Robinow syndrome 1, and available tests. There are links to practice guidelines and authoritative resources like …
WNT-5A: signaling and functions in health and disease
WNT-5A predominantly activates β-catenin-independent WNT signaling cascade but can also activate β-catenin signaling to relay its diverse cellular effects such as cell polarity, migration, …
Wnt5a: A Player in the Pathogenesis of Atherosclerosis and other ...
Wnt5a, a secreted glycoprotein, belongs to a family of highly conserved proteins that regulate important processes such as cell fate specification, embryonic development, cell proliferation, …
Wnt5a is a TLR2/4-ligand that induces tolerance in human
2019年5月9日 · Wnt5a is a signalling protein mainly involved in developmental processes and cancer. The effect of Wnt5a on inflammatory myeloid cells is controversial. Here, we combine …
Wnt5a: A promising therapeutic target for inflammation, …
2023年12月1日 · Wnt5a is a highly evolutionarily conserved non-canonical Wnt ligand on chromosome 3p14-p21 and contains multiple polyadenylation sites. Wnt5a can activate both …
Noncanonical WNT5A controls the activation of latent TGF-
2024年5月15日 · WNT5A was identified as a predominant noncanonical WNT ligand in fibrotic diseases such as systemic sclerosis, sclerodermatous chronic graft-versus-host disease, and …
Wnt5a: its signalling, functions and implication in diseases
2011年3月29日 · Wnt5a is a representative ligand that activates the β-catenin-independent pathways. Because the β-catenin-independent pathway includes multiple signalling cascades …
WNT5A Encodes Two Isoforms with Distinct Functions in Cancers
2013年11月18日 · The mechanism by which WNT5A achieves these distinct activities in cancers is poorly understood. Here, we provide evidence that the WNT5A gene produces two protein …
Biological functions of macrophage-derived Wnt5a, and its roles …
Actually, macrophage-derived Wnt5a maintains macrophage immune function, stimulates pro-inflammatory cytokine release, and induces angiogenesis and lymphangiogenesis. …
WNT5A — Early Detection Research Network
These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a …
WNT5A in tumor development and progression: A comprehensive …
This review focuses on a thorough characterization of the role of WNT5A in neoplastic transformation and progression, which may help to understand the prognostic potentiality of …