V-set domain-containing T-cell activation inhibitor 1 is a protein that in humans is encoded by the VTCN1 gene. [5][6][7] B7H4 belongs to the B7 family (see CD80; MIM 112203) of …

2024年12月25日 · VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1) is a Protein Coding gene. Diseases associated with VTCN1 include Renal Cell Carcinoma and Pancreatic …

2025年1月4日 · Aryl Hydrocarbon Receptor Directly Regulates VTCN1 Gene Expression in MCF-7 Cells. B7-H4 expression promotes non-small cell lung cancer progression via AMPK/mTOR …

VTCN1, a T‐cell regulator, belongs to the immunoglobulin superfamily. It is more highly expressed in tumor tissues than in normal tissues, which suggests that it could serve as a tumor‐related …

2022年11月1日 · VTCN1 is a known negative regulator of T cell response which makes it an astonishing target to be explored in SLE. For the first time, Ramos et al. reported that the …

Recent studies implicated a B7-like negative costimulatory protein, V-set domain-containing T-cell activation inhibitor-1 (VTCN1), as a molecule capable of inhibiting T-cell activation and, …

2024年4月3日 · Altered Levels of Negative Costimulatory Molecule V-Set Domain-Containing T-Cell Activation Inhibitor-1 (VTCN1) and Metalloprotease Nardilysin (NRD1) are Associated …

2022年11月1日 · Targeting autoimmune diseases via immunomodulation has become an essential strategy in today's era. Dysregulation of VTCN1 (V-set domain containing T cell …

2024年1月4日 · Clinical resource with information about VTCN1, Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome-wide association analysis., and …

Highly glycosylated sialomucin; expressed on immune cells. Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and …