VAPB Gene - GeneCards | VAPB Protein | VAPB Antibody
Dec 25, 2024 · VAPB (VAMP Associated Protein B And C) is a Protein Coding gene. Diseases associated with VAPB include Amyotrophic Lateral Sclerosis 8 and Spinal Muscular Atrophy, …
VAPB - Wikipedia
Vesicle-associated membrane protein-associated protein B/C is a protein that in humans is encoded by the VAPB gene. [5] [6] The VAPB gene is found on the 20th human chromosome. …
ER-mitochondria contact sites in neurodegeneration: genetic
Dec 17, 2020 · Vesicle-associated membrane protein B (VAPB) is an ER-residing protein that interacts with protein tyrosine phosphatase-interacting protein-51 (PTPIP51) in the OMM .
VAPB-mediated ER-targeting stabilizes IRS-1 signalosomes to
Aug 1, 2023 · VAPB, an ER-anchored protein that mediates tethers between ER and membranes of other organelles, was identified as a direct interacting partner of IRS-1. VAPB mainly binds …
Secretion of endoplasmic reticulum protein VAPB/ALS8 requires
Oct 10, 2024 · VAMP-associated protein (VAP) is a type IV integral transmembrane protein at the endoplasmic reticulum (ER). Mutations in human VAPB/ALS8 are associated with amyotrophic …
VAP Proteins – From Organelle Tethers to Pathogenic Host …
Vesicle-associated membrane protein (VAMP)-associated proteins (VAPs) are ubiquitous ER-resident tail-anchored membrane proteins in eukaryotic cells. Their N-terminal major sperm …
VAPB VAMP associated protein B and C [ (human)] - National …
VAPB promotes breast tumor growth by modulation of Akt activity. The binding residues have been successfully mapped out on both NS5A and VAPB, thus allowing the construct of the …
The Interactome of the VAP Family of Proteins: An Overview
In this review, we summarize and compare the recent interactome studies described for VAPs, including in silico and proximity labeling methods. Collectively, the interaction repertoire of …
VAPB VAMP associated protein B and C - NIH Genetic Testing …
Mar 5, 2024 · Clinical resource with information about VAPB, Adult-onset proximal spinal muscular atrophy, autosomal dominant, Amyotrophic lateral sclerosis type 8, and available …
《Nature | VAPB的分子运动揭示了ER-线粒体接触位点的亚结构域 …
Jan 29, 2024 · 该研究结合三维电子显微镜与模型细胞器系，囊泡相关膜蛋白（VAMP）相关蛋白B（VAPB）的高速分子跟踪，以绘制ERMCSs的结构和融合现象。 研究人员发现了VAPB接 …