
UREI - Wikipedia
United Recording Electronics Industries (UREI) was a manufacturer of recording, mixing and audio signal processing hardware for the professional recording studio, live sound and broadcasting fields. History
Anti-Helicobacter pylori effectiveness and targeted delivery ...
2018年8月1日 · pylori decreases to a certain range (from neutral to weak acid), the urea channel protein UreI is activated and transfer urea into cytoplasm to produce ammonia to buffer the pH values (Fig. 1 A). The impact of pH parameters on the uptake of FITC-loaded nanoparticles into H. pylori is shown in Fig. 2. The mean floursecence indensity (MFI) of ...
H+-门控尿素通道:幽门螺杆菌尿素酶与胃定植之间的联系,Science …
UreI 是一种内膜蛋白,具有六个跨膜片段,如体外转录/翻译和膜分离所示。 UreI 在非洲爪蟾卵母细胞中的表达导致酸刺激的尿素摄取,其 pH 曲线类似于细胞质尿素酶的激活。
Structure of the proton-gated urea channel from the gastric …
2012年12月9日 · HpUreI was expressed in Escherichia coli cells, then purified and crystallized in a mixture of octylglucoside and decylmaltoside, supplemented with E. coli polar lipids (Avanti). The structure was...
The Helicobacter pylori UreI protein: role in adaptation to
UreI, an inner membrane protein, is essential for resistance to low pH and for the gastric colonization of mice by H. pylori. In the heterologous Xenopus oocytes expression system, UreI behaves like an H+-gated urea channel, and His-123 was found to …
幽门螺杆菌 UreI 蛋白不参与脲酶活性,但对于细菌在体内的存活 …
使用携带非极性 ureI 缺失的小鼠适应型幽门螺杆菌 SS1 菌株进行的实验表明,UreI 对于幽门螺杆菌体内存活和/或小鼠胃定植至关重要。 在 10 mM 尿素存在的情况下,用非极性盒替换 ureI 会大大降低幽门螺杆菌在酸性条件下的存活率(在 pH 2.2 的磷酸盐缓冲盐水溶液 ...
UreI的表达是胃内转运和幽门螺杆菌在沙土胃黏膜定殖所必需的 …
2003年2月1日 · 幽门螺杆菌的野生型或与ureI互补的ureI基因敲除细菌定居于胃腔,而ureI缺失突变体无法定居。 但是,对酸分泌的持续抑制导致ureI突变体在胃中定植,这在野生型菌株中也观察到。
A pH-sensitive channel regulates urea access to Helicobacter …
2000年2月1日 · The Sachs group provides elegant evidence that facilitated urea entry is produced by a pH-sensitive membrane protein encoded by a member of the urease gene family known as UreI. H. pylori in which UreI is deleted cannot survive in acidic medium.
幽门螺杆菌尿素通道蛋白(UreI)研究进展.pdf - 原创力文档
2017年7月30日 · ureA、ureB为尿素酶的两个结构亚单位,它们具有 纳为以下time-independent、acute和chronicresponses三个方面, 高度保守性 ,是PCR检测H.pytori感染常选择的目的基 因; 其中快慢反应都涉及到UreI蛋白通道,快反应与尿素的转运有关, ureC、ureD为调节部分,是表 …
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