
Uridine diphosphate glucuronic acid - Wikipedia
UDP-glucuronic acid is a sugar used in the creation of polysaccharides and is an intermediate in the biosynthesis of ascorbic acid (except in primates and guinea pigs). It also participates in the heme degradation process of human. It is made from UDP-glucose by UDP-glucose 6-dehydrogenase (EC 1.1.1.22) using NAD+ as a cofactor.
Uridine Diphosphate Glucuronic Acid | C15H22N2O18P2 | CID …
UDP-alpha - D-glucuronic acid is a UDP-sugar having alpha-D-glucuronic acid as the sugar component. It has a role as a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is functionally related to an alpha-D-glucuronic acid. It is a conjugate acid of an UDP-alpha-D-glucuronate (3-).
Glucuronosyltransferase - Wikipedia
The glucuronidation reaction consists of the transfer of the glucuronosyl group from uridine 5'-diphospho-glucuronic acid (UDPGA) to substrate molecules that contain oxygen, nitrogen, sulfur or carboxyl functional groups. [5] The resulting glucuronide is more polar (e.g. hydrophilic) and more easily excreted than the substrate molecule.
Uridine 5 -diphosphoglucuronic acid 98-100 43195-60-4
Uridine 5′-diphosphoglucuronic acid (UDPGA) is a cofactor, synthesized from UDPglucose and nicotinamide adenine dinucleotide (NAD +) intracellularly by the catalytic activity of UDPglucose dehydrogenase. The concentration of UDPGA in a number of …
Uridine 5 -diphosphoglucuronic acid 98-100 63700-19-6
Uridine 5′-diphosphate-glucuronic acid (UDP-GlcA) is a carboxylic acid-formed sugar nucleotide. It participates in the biosynthesis of numerous cell components. [3] .
Structure and function of uridine diphosphate ... - PubMed
The uridine diphosphate (UDP)-glucuronosyltransferases (UGT) are a family of enzymes that catalyse the covalent addition of glucuronic acid to a wide range of lipophilic chemicals.
Uridine Diphosphate Glucuronic Acid - ScienceDirect Topics
UDP–glucuronic acid is utilized in biosynthetic reactions that involve condensation of glucuronic acid with a variety of molecules to form an ether (glycoside), an ester, or an amide, depending on the nature of the acceptor molecule. You might find these chapters and articles relevant to this topic. In Dictionary of Toxicology (Third Edition), 2015
Udpga | Sigma-Aldrich
Synonym(s): UDP-GlcA, UDPGA, Uridine-diphosphate-glucuronic acid trisodium salt, Uridine[5′]diphospho[1]-α-D-glucopyranosuronic acid trisodium salt Empirical Formula (Hill Notation) : C 15 H 19 N 2 Na 3 O 18 P 2
Functional characterization and substrate promiscuity analysis of …
2022年10月5日 · Uridine diphosphate glucose dehydrogenase (UGDH) has a crucial role in the synthesis of UDP-glucuronic acid (UDPGA), which is the important sugar donor in the glucuronosylation of bioactive triterpene saponins in the traditional Chinese medicine Glycyrrhiza uralensis Fisch.
Distribution of UDP-glucuronosyltransferase and its endogenous ...
The activity of UDP-glucuronosyltransferase (UDPGT) and the concentration of its endogenous substrate, 5'-diphosphoglucuronic acid (UDPGA), have been measured in human liver, kidney, lung and intestinal mucosa.