2024年12月25日 · ULK1 (Unc-51 Like Autophagy Activating Kinase 1) is a Protein Coding gene. Diseases associated with ULK1 include Overnutrition and Neurodegeneration With Brain Iron …

The ULK1 complex consists of ULK1, FIP200, ATG13 and ATG101 and regulates initiation of autophagosome formation. Lack of one or more ULK1 complex components results in …

The ULK1 complex initiates autophagosome formation, linking cellular nutrient status to downstream events in autophagy. Recent work suggests that the ULK1 complex might also be …

2018年8月28日 · Here, we report that ULK1, a central kinase of the ULK1 complex involved in autophagy initiation, promotes autophagosome–lysosome fusion. PKCα phosphorylates ULK1 …

2021年10月15日 · Here we show that ULK1 phosphorylates the BNIP3 mitochondrial cargo receptor on a critical serine residue (S17) adjacent to its amino terminal LIR motif. ULK1 …

2018年8月9日 · UNC-51-like kinase 1 (ULK1), known as an ortholog of the yeast Atg1, is the serine-threonine kinase and the autophagic initiator in mammals. Accumulating evidence has …

2017年12月12日 · In this artcile, we focus on the regulation of the ULK1 complex during autophagy initiation. The complex pattern of upstream pathways that converge on ULK1 …

ULK1 contributes to mTORC1 inhibition through hindrance of substrate docking to Raptor. ULK1 represents a novel and clinically useful biomarker for esophageal squamous cell carcinoma …

The Atg1/ULK1 complex plays a central role in starvation-induced autophagy, integrating signals from upstream sensors such as MTOR and AMPK and transducing them to the downstream …

Monoclonal Antibody for studying ULK1. Validated for IP, WB, WB. Available in 2 sizes. Highly specific and rigorously validated in-house, ULK1 (D8H5) Rabbit Monoclonal Antibody (CST …