
ULK1 Gene - GeneCards | ULK1 Protein | ULK1 Antibody
2024年12月25日 · ULK1 (Unc-51 Like Autophagy Activating Kinase 1) is a Protein Coding gene. Diseases associated with ULK1 include Overnutrition and Neurodegeneration With Brain Iron …
The mammalian ULK1 complex and autophagy initiation - PMC
The ULK1 complex consists of ULK1, FIP200, ATG13 and ATG101 and regulates initiation of autophagosome formation. Lack of one or more ULK1 complex components results in …
Structure and Function of the ULK1 Complex in Autophagy
The ULK1 complex initiates autophagosome formation, linking cellular nutrient status to downstream events in autophagy. Recent work suggests that the ULK1 complex might also be …
Phosphorylation of ULK1 affects autophagosome fusion and …
2018年8月28日 · Here, we report that ULK1, a central kinase of the ULK1 complex involved in autophagy initiation, promotes autophagosome–lysosome fusion. PKCα phosphorylates ULK1 …
ULK1 promotes mitophagy via phosphorylation and stabilization …
2021年10月15日 · Here we show that ULK1 phosphorylates the BNIP3 mitochondrial cargo receptor on a critical serine residue (S17) adjacent to its amino terminal LIR motif. ULK1 …
UNC-51-like Kinase 1: From an Autophagic Initiator to ... - PubMed
2018年8月9日 · UNC-51-like kinase 1 (ULK1), known as an ortholog of the yeast Atg1, is the serine-threonine kinase and the autophagic initiator in mammals. Accumulating evidence has …
The mammalian ULK1 complex and autophagy initiation
2017年12月12日 · In this artcile, we focus on the regulation of the ULK1 complex during autophagy initiation. The complex pattern of upstream pathways that converge on ULK1 …
ULK1 unc-51 like autophagy activating kinase 1 [ (human)]
ULK1 contributes to mTORC1 inhibition through hindrance of substrate docking to Raptor. ULK1 represents a novel and clinically useful biomarker for esophageal squamous cell carcinoma …
The ULK1 complex: Sensing nutrient signals for autophagy …
The Atg1/ULK1 complex plays a central role in starvation-induced autophagy, integrating signals from upstream sensors such as MTOR and AMPK and transducing them to the downstream …
ULK1 (D8H5) Rabbit mAb | Cell Signaling Technology
Monoclonal Antibody for studying ULK1. Validated for IP, WB, WB. Available in 2 sizes. Highly specific and rigorously validated in-house, ULK1 (D8H5) Rabbit Monoclonal Antibody (CST …
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