Tumor Necrosis Factor (TNF): How Does It Cause Inflammation? - WebMD
2023年11月14日 · Your system gets flooded with inflammation, which often means you have too much tumor necrosis factor – specifically, a type called TNF alpha.
The Role of Tumor Necrosis Factor Alpha (TNF-α) in …
Tumor necrosis factor alpha (TNF-α) is a cytokine that has pleiotropic effects on various cell types. It has been identified as a major regulator of inflammatory responses and is known to be involved in the pathogenesis of some inflammatory and autoimmune diseases .
Tumor necrosis factor - PMC
Tumor necrosis factor (TNF) is a critical cytokine, which contributes to both physiological and pathological processes. This mini-review will briefly touch the history of TNF discovery, its family members and its biological and pathological functions.
Tumor Necrosis Factor Alpha - an overview - ScienceDirect
Tumor Necrosis Factor Alpha (TNF-α) is a cytokine that acts as an arbitrator of the local tissue environment following injury, and is involved in bone tissue regeneration. It can initiate apoptosis and regulate cell survival and proliferation.
Role of tumor necrosis factor-alpha in the central nervous …
Tumor necrosis factor-alpha (TNF-α) is a pleiotropic immune cytokine belonging to the TNF superfamily of receptor ligands. It is involved in several homeostatic and inflammatory processes, and plays a major role in autoimmune and inflammatory diseases (1–3).
Tumor Necrosis Factor-alpha and the Roles it Plays in ... - Springer
2011年7月5日 · Tumor necrosis factor-alpha (TNF-α) is a critical regulatory cytokine exerting both homeostatic and pathophysiological roles in the central nervous system (CNS).
Metabolic Messengers: tumour necrosis factor - Nature
2021年10月14日 · Tumour necrosis factor alpha (TNF-α), also known as TNF superfamily member 2 (TNFSF2) or simply TNF, is a multifunctional cytokine that has well-established immunological roles in innate and ...
Tumor Necrosis Factor Alpha - an overview - ScienceDirect
Tumor necrosis factor alpha (TNF-α) is a cytokine mainly secreted by macrophages that is implicated in immune response regulation and is essential in driving major cellular changes by activating different signaling cascades.
The Role of Tumor Necrosis Factor Alpha (TNF-α) in …
2021年3月8日 · Tumor necrosis factor alpha (TNF-α) was initially recognized as a factor that causes the necrosis of tumors, but it has been recently identified to have additional important functions as a pathological component of autoimmune diseases.
Tumor Necrosis Factor Alpha - an overview - ScienceDirect
Tumor necrosis factor alpha (TNF-α) is a cytokine with pleiotropic actions that can be present both as a transmembrane protein and soluble cytokine (sTNF). Both ligands interact with two different receptors, TNFR1 and TNFR2, which mediate their biological effects.
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