Oct 18, 2023 · TRPM1 and TRPM3 are channels permeable to Ca 2+ and Zn 2+ regulated by neuroactive steroids that have crucial roles in ON-bipolar neurons of the retina, dorsal root …

Feb 23, 2023 · TRPM3-related neurodevelopmental disorder (TRPM3-NDD) is characterized by congenital hypotonia, developmental delay, intellectual disability, seizures, and ophthalmologic …

TRPM3 is dynamically regulated by plasma membrane PI (4,5)P 2 and related PIPs. The transient receptor potential (TRP) channel TRPM3 is a calcium-permeable cation channel activated by …

Transient Receptor Potential Melastatin 3 (TRPM3) is a Ca 2+ permeable nonselective cation channel, activated by heat and chemical agonists, such as the endogenous neuro-steroid …

Dec 25, 2024 · TRPM3 (Transient Receptor Potential Cation Channel Subfamily M Member 3) is a Protein Coding gene. Diseases associated with TRPM3 include Cataract 50 With Or Without …

Feb 26, 2021 · However, recent research identifies TRPM3 as an emerging new player in the brain. In this review, we summarize the available data regarding the roles of TRPM3 in the …

Jan 14, 2025 · Transient receptor potential channel subfamily M member 3 (TRPM3) is a Ca 2+ -permeable cation channel activated by the neurosteroid pregnenolone sulfate (PregS) or heat, …

Jan 17, 2023 · Newly identified gain-of-function variants indicate TRPM3 as the cause of a spectrum of autosomal dominant neurodevelopmental disorders with frequent cerebellar …

Feb 28, 2025 · The TRPM3 Foundation focuses on building community among patients and their families, caregivers, and healthcare providers, as well as funding of innovative research to …

Feb 17, 2023 · TRPM3, unlike other TRPM channels, is activated by sphingosine (review by Farooqi et al., 2011). TRPM3 is activated by heat and is highly expressed in nociceptor …