2024年9月1日 · In order to elucidate the relationship between pretreatment radiomic parameters and the proportions of various tumor-infiltrating (TI) cells, we retrospectively analyzed the association of total metabolic tumor volume (TMTV) and TI cells on biopsied tumor lesions in 171 patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL).

New volume-based parameters derived from baseline 18 F-FDG PET/CT, such as total metabolic tumor volume (TMTV) and total lesion glycolysis (TLG), can reflect metabolic volume and activity and have been proposed as quantitative indexes of tumor metabolism biomarkers in Hodgkin’s and B-cell lymphomas [8].

2024年2月8日 · Total metabolic tumor volume (TMTV) segmentation has significant value enabling quantitative imaging biomarkers for lymphoma management. In this work, we tackle the challenging task of automated tumor delineation in lymphoma from PET/CT scans using a cascaded approach. Our study included 1418 2-[18F]FDG …

High total metabolic tumor volume (TMTV), computed from baseline 18 F-fluorodeoxyglucose–positron emission tomography (PET), is associated with shorter progression-free survival (PFS), but circulating tumor cells (CTCs) and cell-free DNA (cfDNA) may also reflect tumor burden and be of prognostic value.

2022年7月7日 · TMTV, TLG, and SUV max were centrally determined by three experienced nuclear medicine physicians from each baseline PET/CT scan collected in real time during the study. TMTV was calculated using a tumor threshold of 1.5 times the mean SUV of the liver +2 standard deviations.

TMTV was able to separate patients with a high-risk NCCN-IPI of ≥4 (n = 62) into two groups with significantly different outcomes; patients with low TMTV (n = 16) had a 3-year PFS rate of 75% and an OS rate of 88%, while those with a high TMTV had a 3-year PFS rate of 32% and an OS rate of 47% (χ 2 = 7.92, P = 0.005, and χ 2 = 8.26, P = 0. ...

2024年2月8日 · Purpose Total metabolic tumor volume (TMTV) segmentation has significant value enabling quantitative imaging biomarkers for lymphoma management. In this work, we tackle the...

Танин Мэдэхүй телевиз нь 2006 оны 4 сарын 01-нд анхны нэвтрүүлгээ бэлтгэж үзэгч олондоо хүргэснээс хойш байнгын үйл ажиллагаатай болж өдөр бүр 08:00 - 24:00 цагийн хооронд тогтмол эфир явуулсаар байна. Дэлгэрэнгүй...

High baseline TMTV (±ECOG) was a strong prognosticator of inferior PFS and OS in REMARC patients post-R-CHOP, irrespective of maintenance. Early identification of ultra-risk diffuse large B-cell lymphoma (DLBCL) patients is needed to aid stratification to innovative treatment.

2016年7月31日 · New promising PET metrics derived from baseline PET, allowing an estimate of tumor burden and metabolism, are proposed as biomarkers: the total metabolic tumor volume (TMTV) which is the sum of the regions of the local tumors with FDG uptake; the total lesion glycolysis (TLG) which is the sum of these regions weighted by the intensity of their F...