Toll-like receptors (TLRs) are recognition molecules for multiple pathogens, including bacteria, viruses, fungi, and parasites. TLR2 forms heterodimers with TLR1 and TLR6, which is the …

In this review, we provide an up-to-date overview of TLR2, including its homo- and heterodimers. Furthermore, we will discuss the pro- and anti-inflammatory properties of TLR2 and recent …

Dec 25, 2024 · TLR2 (Toll Like Receptor 2) is a Protein Coding gene. Diseases associated with TLR2 include Leprosy 3 and Colorectal Cancer. Among its related pathways are Toll Like …

Toll-like receptors (TLRs) are the important mediators of inflammatory pathways in the gut which play a major role in mediating the immune responses towards a wide variety of pathogen …

TLR2 is a key innate immune receptor that recognizes a diverse array of conserved ligands on pathogens and also endogenous ‘alarmins’. TLR2 signaling is initiated by heterodimerization …

Apr 9, 2024 · Cell surface TLRs (TLR1, TLR2, TLR4, and TLR5) recognize lipid and protein components, whereas endosomal TLRs (TLR3, TLR7, TLR8, TLR9, and TLR13) specialize in …

Toll-like receptor (TLR) 2 is a member of the vertebrate protein family of TLRs that has been studied in substantial detail over the last years. The extracellular domain of the type I receptor …

Gene ID: 7097, updated on 8-Feb-2025. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and …

Jan 19, 2021 · In this issue of Science Signaling, McCoy et al. reveal a new role of TLR2 in endothelial cells, where it promotes tumor angiogenesis, infiltration of myeloid cells, and, …

Apr 17, 2012 · TLR2 forms heterodimers with TLR1 and TLR6, which is the initial step in a cascade of events leading to significant innate immune responses, development of adaptive …