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What Is Therapeutic Index And Why Is It Important For Drugs
2017年11月21日 · The therapeutic index comes out to 1.2 (60 mg/50 mg). For Drug Y, the therapeutic dose and lethal dose are much farther apart. The therapeutic index comes out to 16 (800 mg/50 mg). According to the therapeutic index of Drug X and Drug Y, Drug Y is safer and has a larger window of safety.
How To Get The Same Brand Of Levothyroxine Every Time
2018年4月2日 · Levothyroxine is known as a narrow therapeutic index drug. A small change in dose can have a major impact on how the medication affects you. Remember that the dose of levothyroxine is dosed in micrograms, which is one one-thousandths of a milligram! The doses are extremely small.
Zyrtec With Lithium Interaction - Walrus Health
2018年11月8日 · Although lithium can be very effective, it requires close monitoring due to its narrow therapeutic range and risk of toxicity. Lithium toxicity is closely related to blood lithium concentrations and can occur at doses close to therapeutic concentrations. Blood lithium concentrations, electrolytes, and kidney function need to be routinely checked.
Does Lithium Interact With Turmeric And Bioperine? - Walrus Health
2019年5月13日 · The means that there is a very fine line between sub-therapeutic, therapeutic and toxic levels. [5] As it concerns turmeric with Bioperine (a patented black pepper extract), there are no documented case studies in which an interaction with lithium has been observed, but that doesn't necessarily mean there aren't any.
Taking Benadryl With Levothyroxine - Walrus Health
2018年4月2日 · Levothyroxine is known as a narrow therapeutic index drug, meaning there is a small window of effectiveness in regard to dose. It is important to stay on the same generic manufacturer of levothyroxine to reduce the variability between products.
What Is The Difference Between Brand And Generic Drugs?
2017年9月22日 · There is some controversy surrounding this, but one situation where it may be prudent to stay on a brand name drug is if you have already been taking it (i.e. are stable on it) and the drug is considered a 'narrow-therapeutic index drug. These drugs are used for disease states where a small change in dose can make a big difference in effect ...
Taking Diclofenac With Synthroid - Walrus Health
2019年4月9日 · The reason we are so concerned with how Synthroid should be taken is that it is considered a narrow therapeutic index drug. This means that there is a small margin between therapeutic, sub-therapeutic and toxic doses. Remember that Synthroid doses are measured in micrograms, which is 1/1000th of one milligram! We are talking very small doses here.
Can You Take Levothyroxine At Night? - Walrus Health
2017年12月14日 · Levothyroxine is considered a narrow therapeutic index drug, meaning small changes in dose can result in large differences in drug efficacy. Levothyroxine is dosed in micrograms, not milligrams, giving you an idea of how small these doses are. Even a small difference in the absorption of the drug can make a big difference.
Can Duexis Be Crushed? - Walrus Health
2017年9月25日 · Mildrend asked. Can Duexis be crushed? Answer. Unfortunately, Duexis must be taken as a whole tablet and cannot be split, divided, chewed, or crushed per the package insert of Duexis.
A Pharmacist's Thoughts On Pharmacogenomics Testing - Walrus …
2018年1月31日 · Because of its narrow therapeutic index, where prescribers must balance the chance of clotting versus the risk of bleeding, warfarin dosing is critical to get right for each patient. Testing patients for CYP2C9 and VKORC1 variants can help make more informed dosing decisions during patient therapy, although guidelines do not currently support ...