tert-Butyldimethylsilyl chloride is an organosilicon compound with the formula (Me 3 C)Me 2 SiCl (Me = CH 3). It is commonly abbreviated as TBSCl or TBDMSCl. It is a chlorosilane containing …

Tert-butyldimethylsilyl chloride is a silyl chloride consisting of a central silicon atom covalently bound to one chloro, one tert-butyl and two methyl groups. tert-Butyldimethylsilyl chloride is a …

2025年2月24日 · tert-Butyldimethylchlorosilane is used to protect hydroxyl group in organic synthesis. It finds application in the synthesis of prostaglandin. It is also used as an auxiliary …

tert -Butyldimethylsilyl chloride (TBDMSCl) is an organosilicon compound that can be used as a versatile protecting reagent for alcohols, amines, amides, and various carboxylic acids. [1] [2] …

TBS protection by Corey uses TBS-Cl (forms hygroscopic white crystals) in DMF with imidazole or DMAP. Corey encountered challenges using TBS-Cl for protection of tertiary or hindered …

叔丁基二甲基氯硅烷 (TBDMSCl) 是一种常用的硅烷化剂，是有机合成中应用最为广泛的重要保护基之一。 在核糖核苷的合成中用于羟基的保护基，同时也是氧化剂，脱氰剂。 它可以在温和 …

tert-Butyldimethylsilyl chloride is an organosilicon compound with the formula (Me 3 C)Me 2 SiCl (Me = CH 3). It is commonly abbreviated as TBSCl or TBDMSCl. It is a chlorosilane containing …

1-フェニルエタン-1,2-ジオール (276 mg, 2.0 mmol)のジクロロメタン (4 mL, 0.5 mol/L)溶液に トリエチルアミン (0.416 mL, 3.0 mmol)， (362 mg, 2.4 mmol)を加えた後、さらに DMAP …

tert-Butyldimethylsilylchlorid (kurz: TBDMSCl; oft auch weiter verkürzend TBSCl) ist eine chemische Verbindung, die dazu dient, TBS- Schutzgruppen einzuführen. Eine einfache …

When the commercially available tert -butyldimethylsilyl chloride (TBDMS-Cl) was initially used as a silylation agent, it was found by E. J. Corey (J. Am. Chem. Soc. 1972, 94, 6192) to react …