Targeted drug delivery - Wikipedia
There are two kinds of targeted drug delivery: active targeted drug delivery, such as some antibody medications, and passive targeted drug delivery, such as the enhanced permeability and retention effect (EPR-effect).
The targeted drug delivery systems have several advantages over conventional ones as improvement of pharmaceutical activity, low side effects and reduction of the administered dose.
Targeted drug delivery strategies for precision medicines
The key in the design of a targeted drug carrier is knowledge of the specific drug’s main problems, which may include its pharmacokinetics, biodistribution, on-target toxicities, off-target toxicities (especially dose-limiting toxicities), and drug resistance.
Drug Delivery Systems - National Institute of Biomedical Imaging …
Some common examples of drug delivery vehicles include micelles, liposomes, or nanoparticles. Different drug delivery vehicles can improve the targeting of the drug by helping the medication travel exactly where it needs to go.
Targeted Drug Delivery - an overview | ScienceDirect Topics
Targeted drug delivery systems (DDSs) are designed to transport drugs or therapeutic agents to specific tissue in, protecting them from degradation, maintaining optimal drug concentration, and minimizing adverse drug-effects.
Advances in drug delivery systems, challenges and future directions
2023年6月1日 · Recent drug delivery systems (DDS) are formulated using advanced technology to accelerate systemic drug delivery to the specific target site, maximizing therapeutic efficacy and minimizing off-target accumulation in the body.
Different Targeting Ligands-Mediated Drug Delivery Systems for …
This review focuses on the research progress of targeted drug delivery systems based on different targeting ligand-mediated delivery systems, including folic acid, carbohydrates, peptides, aptamers, and antibodies.
Cell-mediated targeting drugs delivery systems - PMC - PubMed …
Cell-mediated DDS has become a new field of medicine, which enables the targeted delivery, prolongation of circulation time while reducing cellular and tissue toxicities. This system for drug delivery and targeted release represents a novel disease-fighting strategy for a …
Minuscule Robots for Targeted Drug Delivery - www.caltech.edu
6 天之前 · The final stage of development involved testing the microrobots as a drug-delivery tool in mice with bladder tumors. The researchers found that four deliveries of therapeutics provided by the microrobots over the course of 21 days was more effective at shrinking tumors than a therapeutic not delivered by robots.
Targeted Drug Delivery - an overview | ScienceDirect Topics
A targeted drug delivery system should have four features: retaining, evading, targeting, and releasing. Drugs should be efficiently loaded in a suitable vehicle, which is capable of eluding the body’s secretions.