The transient receptor potential cation channel subfamily V member 1 (TRPV1), also known as the capsaicin receptor and the vanilloid receptor 1, is a protein that, in humans, is encoded by …

TRPV1 is a key bridge in neuroimmune interactions, allowing for smooth and convenient communication between the two systems. Here, we discuss the coordinated cross-talking …

TRPV1 consists of six transmembrane domains with a pore region between the fifth and sixth domain, and long intracellular N- and C- terminal tails. Within the N-terminal tail, six ankyrin …

2017年5月10日 · We found that stimulation of microglial TRPV1 controls cortical microglia activation per se and indirectly enhances glutamatergic transmission in neurons by promoting …

This review will discuss the expression, functionality and roles of these non-neuronal TRP channels away from sensory nerves to demonstrate the diverse nature of TRPV1 and TRPA1 …

TRPV1 is a prognostic marker in Liver hepatocellular carcinoma, Pancreatic adenocarcinoma

2020年4月1日 · TRPV1 is mainly expressed by trigeminal ganglion (TG) neurons and by small-diameter neurons within sensory ganglia such as the dorsal root ganglion (DRG).

2017年8月29日 · Biophysical analyses of TRPV1 constructs reveal that the S5-pore helix loop influences protein stability and vanilloid and proton responses, but not thermal sensitivity.

Nociceptor neurons, expressing Trpv1, elicited the broadest immunomodulation, inducing changes in innate lymphocytes, macrophages, and RORγ + regulatory T (T reg) cells.

2024年5月1日 · Transient receptor potential vanilloid 1 (TRPV1) senses varied noxious stimuli. TRPV1 activation allows the passage of cations, especially calcium. TRPV1 is involved in …