TRPC1 was the first mammalian Transient Receptor Potential channel to be identified. In 1995 it was cloned when the research groups headed by Craig Montell and Lutz Birnbaumer were …

TRPC1 knockdown studies show that inhibition of TRPC1 leads to improved motor performance and rescued medium spiny neurons spines in vitro and in vivo . TRPC channels are also …

Dec 25, 2024 · TRPC1 (Transient Receptor Potential Cation Channel Subfamily C Member 1) is a Protein Coding gene. Diseases associated with TRPC1 include Pyloric Stenosis and T Cell …

TRPC1 and Orai1 form discrete STIM1-gated channels that generate distinct Ca 2+ signals and regulate specific cellular functions. Surface expression of TRPC1 can be modulated by …

One known link of TRPC1 to cancer progression is that TRPC1 is a downstream effector of the TGFβ signaling. TGFβ plays a role in modulating a key step in tumor invasion and metastasis, …

TRPC1 associates with BK(Ca) channel to form a signal complex in vascular smooth muscle cells. Store-operated Ca(2+) entry in platelets occurs independently of transient receptor potential …

Transient receptor potential canonical (TRPC) channels constitute a group of receptor-operated calcium-permeable nonselective cation channels of the TRP superfamily. The seven …