Taste receptor 2 member 38 is a protein that in humans is encoded by the TAS2R38 gene. TAS2R38 is a bitter taste receptor; varying genotypes of TAS2R38 influence the ability to taste both 6-n-propylthiouracil (PROP) [5] and phenylthiocarbamide (PTC).

May 3, 2016 · The ability to taste phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) is a polymorphic trait mediated by the TAS2R38 bitter taste receptor gene.

Dec 2, 2019 · Here we evaluated the role of the bitter receptor TAS2R38 in attainment of longevity, since it has been widely associated with individual differences in taste perception, food preferences, diet,...

Jul 25, 2019 · TAS2R38 is known as the bitter taste gene and it affects an individual’s response to taste bitter foods, with polymorphisms in the bitter taste receptor gene (TAS2R38) altering the ability to sense the intensity of bitterness of phenylthiocarbamide (PTC) and 6 …

Mar 8, 2025 · TAS2R38 is a novel modifier gene in patients with cystic fibrosis. TAS2R38 bitter taste receptor and attainment of exceptional longevity.

The human TAS2R38 gene encodes a bitter taste receptor that regulates the bitterness perception and differentiation of ingested nutritional/poisonous compounds in the oral cavity and gastrointestinal tract.

Dec 25, 2024 · TAS2R38 (Taste 2 Receptor Member 38) is a Protein Coding gene. Diseases associated with TAS2R38 include Thiourea Tasting and Dental Caries. Among its related pathways are GPCR downstream signalling and Sensory perception of taste.

Our findings show that a simple PTC filter paper tasting method strongly predicts TAS2R38 genotype, and that the genotype-phenotype association is similar among ethnocultural groups.

Nov 2, 2024 · Genotype-specific regulation of oral innate immunity by T2R38 taste receptor. T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection. Genetics of the taste receptor T2R38 correlates with …

TAS2R38 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (summary by Conte et al., 2002). For further information on the TAS2R gene family, see 604791.