- The polypeptide fold of the major capsid protein VP2 is a ‘‘jelly roll’’ with a -barrel motif similar to that found in many icosahedral viruses. The large loops connecting the strands of the -barrel form surface features that differentiate B19 from other parvoviruses.Learn more:The polypeptide fold of the major capsid protein VP2 is a ‘‘jelly roll’’ with a -barrel motif similar to that found in many icosahedral viruses. The large loops connecting the strands of the -barrel form surface features that differentiate B19 from other parvoviruses.www.pnas.org/doi/pdf/10.1073/pnas.0402992101Human parvovirus B19 is the only parvovirus known to be a human pathogen. The structure of recombinant B19-like particles has been determined to ≈3.5-Å resolution by x-ray crystallography and, to our knowledge, represents the first near-atomic structure of an Erythrovirus.pmc.ncbi.nlm.nih.gov/articles/PMC511008/
Parvovirus B19: Structure, Transmission, and Immune Response
Oct 10, 2024 · Exploring Parvovirus B19 involves examining its structural components, transmission routes, cellular entry mechanisms, host immune response, diagnostic methods, and ongoing research. Each area offers insights into managing and mitigating the effects of this virus.
The structure of human parvovirus B19 - PNAS
Aug 2, 2004 · Human parvovirus B19 is the only parvovirus known to be a human pathogen. The structure of recombinant B19-like particles has been determined to ≈3.5-Å resolution by x-ray crystallography and, to our knowledge, represents …
- Studies of Structure Du Parvovirus B19
The structure of human parvovirus B19 - PMC - PubMed Central …
Human parvovirus B19 is the only parvovirus known to be a human pathogen. The structure of recombinant B19-like particles has been determined to ≈3.5-Å resolution by x-ray …
The Structures and Functions of Parvovirus Capsids and …
The parvovirus capsid is a potent antigen, and the sites of anticapsid antibody binding to porcine parvovirus (PPV), waterfowl parvoviruses (WPV), B19, AAV, CPV, and FPV have been defined. In PPV, two monoclonal antibodies (MAbs) …
Human Parvovirus B19 - PMC
Parvovirus B19 (B19) was discovered serendipitously in 1974 and is the only member of the family Parvoviridae known to be pathogenic in humans. The virus is widespread, and …
- bing.com › videosWatch full videoWatch full video
1S58: The structure of B19 parvovirus capsid - RCSB PDB
Jan 20, 2004 · Human parvovirus B19 is the only parvovirus known to be a human pathogen. The structure of recombinant B19-like particles has been determined to approximately 3.5-A resolution by x-ray crystallography and, to …
Structure of Parvovirus B19 Decorated by Fabs from a Human …
We have determined and report here the high-resolution structure of B19 virus-like particles (VLPs) complexed with the Fab of a human neutralizing antibody. The structure shows a …
Human parvovirus B19: a mechanistic overview of …
Nov 1, 2021 · Human parvovirus B19 (B19V) is a human pathogen that belongs to genus Erythroparvovirus of the Parvoviridae family, which is composed of a group of small DNA viruses with a linear single-stranded DNA genome. B19V …
Structure of Parvovirus B19 Decorated by Fabs from a Human
Apr 17, 2019 · We have determined and report here the high-resolution structure of B19 virus-like particles (VLPs) complexed with the Fab of a human neutralizing antibody. The structure …
The structure of human parvovirus B19 - PubMed
Aug 10, 2004 · Human parvovirus B19 is the only parvovirus known to be a human pathogen. The structure of recombinant B19-like particles has been determined to approximately 3.5-A …