Dec 25, 2024 · SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2) is a Protein Coding gene. Diseases associated with SREBF2 include Hypercholesterolemia, Familial, 1 …

Vergnes et al. reveal how loss of Srebp2 (Srebf2) in the mouse greatly compromises expression of both Srebp1a and Srebp1c in the liver (asterisk), which are cotranscribed from the same …

Mar 4, 2025 · Title: Dominant missense variants in SREBF2 are associated with complex dermatological, neurological, and skeletal abnormalities. Hyperactivation of SREBP induces …

Three homozygous variants (p.L604W, p.S517F, and p.T984A) within the sterol regulatory element-binding factor 2 (SREBF2) gene are identified in one autosomal recessive family and …

Sep 12, 2022 · Chromatin immunoprecipitation sequencing (ChIP-seq) analyses reveals that sterol regulatory element-binding proteins (SREBPs), the master regulatory TFs of lipid …

Nov 29, 2023 · Cholesterol homeostasis is under tight regulation at the transcriptional and post-transcriptional level. Sterol regulatory element-binding protein 2 (SREBP2, encoded by the …

Jan 21, 2016 · Vergnes et al. reveal how loss of Srebp2 (Srebf2) in the mouse greatly compromises expression of both Srebp1a and Srebp1c in the liver (asterisk), which are …

Mar 2, 2011 · The sterol regulatory element-binding factor-2 (SREBF2) gene is a bifunctional locus encoding SREBP-2, a well-known transcriptional regulator of genes involved in …

SREBF2 is a prognostic marker in Kidney renal clear cell carcinoma, Lung squamous cell carcinoma

Overexpression of sterol regulatory element-binding factor (Srebf2) in transgenic animals is linked to elevated cholesterol levels and diabetes development.