2024年12月25日 · SOX1 (SRY-Box Transcription Factor 1) is a Protein Coding gene. Diseases associated with SOX1 include Lambert-Eaton Myasthenic Syndrome and Bilateral Hypoactive …

SOX1 is a gene that encodes a transcription factor with a HMG-box (high mobility group) DNA-binding domain and functions primarily in neurogenesis. SOX1, SOX2 and SOX3, members of …

SOX1 is one of the earliest TFs expressed in cells committed to the neural fate. Its expression correlates with the formation of neural plate, while down-regulation of Sox1 expression in the …

Anti-Sry-like high mobility group box (SOX) 1 antibodies (abs) are partly characterized onconeural autoantibodies (autoabs) due to their correlation with neoplastic diseases. Anti-SOX1 abs are …

Data show that high levels of SRY-box transcription factor 1 (SOX1) observed in a subset of patients correlate with lower overall survival, and suggest SOX1 as a potential target in the …

SOX1 plays many roles in embryogenesis, oncogenesis, and male sex determination, and can promote glioma stem cell proliferation, invasion, and migration due to its high expression in …

We demonstrate a role for SOX1 in neural determination and differentiation using an inducible expression P19 cell system as an in vitro model of neurogenesis. Misexpression of SOX1 can …

Objective: To describe the clinical associations of SOX1 antibodies (SOX1-Abs), determine the accuracy of various detection techniques, and propose laboratory criteria to identify definite …

2004年5月15日 · Sox1 binds directly to the Hes1 promoter and suppresses Hes1 transcription, thus attenuating Notch signaling. Sox1 also binds to β-catenin and suppresses β-catenin …

First, most Sox factors are expressed in multiple types of stem/progenitor cell types or tissues. Second, many Sox factors act redundantly in the maintenance of stem cells (e.g., Sox1, Sox2, …