Apr 27, 2021 · SMARCA4 (BRG1), SMARCA2 (BRM) or SMARCB1 (INI1) aberrant loss (Dis Esophagus 2009;22:1, Am J Surg Pathol 2021;45:414) Sample pathology report Esophagus, …

Jun 1, 2022 · SMARCB1 (switch / sucrose non fermentable [SWI / SNF] related, matrix associated, actin dependent regulator of chromatin subfamily B member 1) is located on …

O-Z: perivascular epithelioid cell tumor (PEComa) POLE ultramutated endometrial carcinoma progestin therapy related changes serous carcinoma SMARCA4 deficient uterine sarcoma …

Jun 21, 2023 · 4 genetically defined groups and 4 histologically defined groups (Nature 2017;547:311) Genetically defined: (a) WNT (for wingless integration site) activated, (b) SHH …

Soft tissue: AE1 / AE3 ALK1 caldesmon CAMTA1 CCNB3 (pending) CD31 CD34 CD99 CDK4 D2-40 DDIT3 (pending) desmin DOG1 DUX4 EBER EMA ERG factor XIIIa FLI1 FOSB …

Jul 11, 2024 · SMARCA4 deficient carcinomas are histologically undifferentiated, composed of large epithelioid anaplastic cells in nests and trabeculae; diffuse loss of BRG1 staining by IHC …

Aug 29, 2024 · Comment: The biopsy shows mixture of epithelial, mesenchymal and neuroepithelial components. The presence of fetal-like clear cell appearance in the epithelial …

Aug 8, 2023 · Squamous cell carcinoma is a malignant tumor arising from epithelial cells with squamous differentiation demonstrated either immunohistochemically or morphologically, with …

Aug 26, 2021 · Sertoli-Leydig cell tumor is a rare ovarian tumor composed of sex cord (Sertoli cells) and stromal (Leydig cells) elements, accounting for < 0.5% of all ovarian neoplasms

BAP1 is functionally a tumor suppressor (Proc Natl Acad Sci USA 2014;111:285) BAP1 is a deubiquitinase that associates with multiprotein complexes that regulate key cellular pathways, …