2024年12月25日 · SLC7A5 (Solute Carrier Family 7 Member 5) is a Protein Coding gene. Diseases associated with SLC7A5 include Respiratory System Cancer and Lysinuric Protein …

2021年1月7日 · We show that concomitant mutation of Apc and Kras in the mouse intestinal epithelium profoundly rewires metabolism, increasing glutamine consumption. Furthermore, …

Here, we show that the amino acid transporter Slc7a5 / Lat1 is highly expressed in tissues undergoing morphogenesis and that Slc7a5 ‐null mouse embryos have profound neural and …

2018年6月22日 · SLC7A5, known as LAT1, belongs to the APC superfamily and forms a heterodimeric amino acid transporter interacting with the glycoprotein CD98 (SLC3A2) through …

We show that concomitant mutation of Apc and Kras in the mouse intestinal epithelium profoundly rewires metabolism, increasing glutamine consumption. Furthermore, SLC7A5, a glutamine …

2020年11月4日 · Pathogenic mutations in the solute carrier family 7 member 5 (SLC7A5) gene, which encodes an amino acid transporter cause microcephaly and seizures, yet the …

SLC7A5 is an antiporter that can export glutamine, 40 and intracellular glutamine levels were increased in SLC7A5 KO cell lines in arginine-free media (Figures S2D and S2E). We next …

Study shows that the solute carrier transporter 7a5 (SLC7A5), a large neutral amino acid transporter localized at the blood brain barrier (BBB), has an essential role in maintaining …

2022年10月2日 · SLC7A5 mediates large neutral amino acids transportation across plasma membrane in a Na+ independent manner, which supplies essential amino acid for somatic …

The amino acid transporter named solute carrier family 7 member 5 (SLC7A5) is suggested to play a part in altered cell metabolism and proliferative signaling and has been reported to be …