SLC16A3 Gene - GeneCards | MOT4 Protein | MOT4 Antibody
2024年12月25日 · SLC16A3 (Solute Carrier Family 16 Member 3) is a Protein Coding gene. Diseases associated with SLC16A3 include Autism Spectrum Disorder and Hyperinsulinemic …
Monocarboxylate transporter 4 - Wikipedia
Monocarboxylate transporter 4 (MCT4) also known as solute carrier family 16 member 3 is a protein that in humans is encoded by the SLC16A3 gene. [ 5 ] [ 6 ] Northern and western …
Mechanistic basis of L-lactate transport in the SLC16 solute ... - Nature
2019年6月14日 · MCT4 (SLC16A3), which is strongly overexpressed in highly glycolytic and anaerobic tissues, has a low affinity for l-lactate (K m 20–35 mM) and is responsible for L …
SLC16 Family: From Atomic Structure to Human Disease
2021年1月1日 · The focus of this review is to highlight novel structural insights obtained from X-ray structures of an L-lactate-transporting SLC16 family homolog. Furthermore, the roles of …
Cancer cell | 樊嘉/周虎/高大明/高强又一力作：多组学联合绘制肝 …
2022年2月10日 · 其中，hkdc1是最显著的预后正相关蛋白，slc16a3是最显著的预后负相关蛋白 （图7b） 。 这两种蛋白的丰度在四个 蛋白质组 亚型中也存在显著差异，SLC16A3在S1中上 …
Monocarboxylate Transporters (SLC16): Function, Regulation, and …
The solute carrier family 16 (SLC16) is comprised of 14 members of the monocarboxylate transporter (MCT) family that play an essential role in the transport of important cell nutrients …
溶质载体家族 16 成员 3（SLC16A3）基因 | MCE
质子连接的单羧酸转运蛋白 (MCT) 家族成员催化乳酸和丙酮酸跨质膜转运，该家族已被指定为溶质载体家族 16。 每种 MCT 似乎具有略微不同的底物和抑制剂特异性以及转运动力学，这与其 …
乳酸转运蛋白 SLC16A3 (MCT4) 作为与肺癌中肿瘤微环境和免疫反 …
高 SLC16A3 与 LUAD 而非 LUSC 中的免疫抑制细胞（Treg、Th2 和 iDC）、免疫检查点（PD1、PD-L1、PVR、Tim-3、ITGAM）和免疫抑制因子（foxp3、TGF-β）相关。 此外，SLC16A3 与 …
SLC16A3 solute carrier family 16 member 3 [ (human)]
Targeting tumor-intrinsic SLC16A3 to enhance anti-PD-1 efficacy via tumor immune microenvironment reprogramming. Involvement of SLC16A1/MCT1 and SLC16A3/MCT4 in l …
The SLC16 gene family - structure, role and regulation in ... - PubMed
The SLC16 gene family has fourteen members. Four (SLC16A1, SLC16A3, SLC16A7, and SLC16A8) encode monocarboxylate transporters (MCT1, MCT4, MCT2, and MCT3, …