SIRPγ: an important checkpoint of human effector T-cells
Signal regulatory protein g (SIRPγ) is uniquely expressed by human T-cells, compared to other immunomodulatory SIRP family members. The role of SIRPγ in T cell function is largely …
Signal-regulatory protein alpha - Wikipedia
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells [citation needed] or neurons. SIRPα …
SIRPγ-expressing cancer stem-like cells promote immune escape …
2022年3月1日 · Here we showed that signal regulatory protein γ (SIRPγ) determined CSLC properties and immune evasiveness in a small population of lung adenocarcinoma (LUAD) …
The SIRP family of receptors and immune regulation
2006年5月12日 · Members of the signal-regulatory protein (SIRP) family, which are expressed mainly by myeloid cells, provide one example of these regulatory membrane proteins. There …
信号调节蛋白γ（SIRPG）基因 | MCE - MCE-生物活性分子大师
信号调节蛋白γ： 该基因编码的蛋白质是信号调节蛋白 (sirp) 家族的一员，也属于免疫球蛋白超家族。 sirp 家族成员是受体型跨膜糖蛋白，已知参与受体酪氨酸激酶偶联信号传导过程的负调节 …
Molecular functions of SIRPα and its role in cancer - PMC
The signal regulatory protein (SIRP) family consists of an inhibitory receptor, SIRPα, an activating receptor, SIRPβ [also known as cluster of differentiation (CD)172b] and a non-signaling …
Soluble SIRP-Alpha Promotes Murine Acute Lung Injury Through ...
Soluble signal regulatory protein-alpha (SIRP-alpha) is elevated in bronchoalveolar lavage (BAL) of mice with lipopolysaccharides (LPS)-induced acute lung injury (ALI). To define the role of …
别吃我信号SIRPα/CD47肿瘤靶点的研究 - 知乎 - 知乎专栏
SIRPα (Signal regulatory proteinα)是SIRP家族中的一个典型的抑制性免疫受体，其可以选择性地表达于髓系细胞和神经细胞膜表面； CD47 是一种各种细胞广泛表达的类Ig膜蛋白，可与多种 …
Prostate cancer downregulated SIRP-α modulates apoptosis and ...
The present study investigated the regulatory mechanism of signal-regulatory protein (SIRP)-α in the apoptosis and proliferation of prostate cancer (CaP) cells. The expression profile of SIRP …
Roleplay - SIRP
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