Silk fibroin (SF), extracted mainly from silkworms, has become a popular biomaterial due to its excellent biocompatibility, exceptional mechanical properties, tunable degradation, ease of processing, and sufficient supply.

2015年7月1日 · In this review, we describe the current understandings of the constituents, structures, and mechanical properties of silk fibroin. Following that, we summarize the strategies to bring its mechanical performance closer to that of spider dragline silk.

Fibroin is known to arrange itself in three structures, called silk I, II, and III. Silk I is the natural form of fibroin, as emitted from the Bombyx mori silk glands. Silk II refers to the arrangement of fibroin molecules in spun silk, which has greater strength and is often used in various commercial applications. Silk III is a newly ...

2024年3月20日 · Silk fibroin (SF) belongs to a distinct class of glycoproteins, and its structure is characterized by a heavy chain (Hc) with an approximate molecular weight (MW) of 350 kDa and a light chain (Lc) of about 25 kDa, which are linked …

2016年9月7日 · In this study, we report the structures of silk fibroin before and after spinning, determined by solution and solid-state nuclear magnetic resonance (NMR). The pre-spinning structure of...

A repeated β-turn structure in Poly(Ala-Gly) as a model for silk I of Bombyx mori silk fibroin studied with two-dimensional spin-diffusion NMR under off magic angle spinning and rotational echo double resonance.

2011年10月20日 · Fibroins serve as the major building blocks of silk fiber. As the major component of fibroin, the fibroin heavy chain is a considerably large protein comprising N-terminal and C-terminal hydrophilic domains and 12 highly repetitive Gly-Ala-rich regions flanked by internal hydrophilic blocks.