Apr 24, 2024 · 可溶性SEMA7A分别通过诱导T-bet和RORγt表达促进CD4+T分化为Th1和Th17两种亚型，并可启动T细胞介导的炎症反应。 在胃肠道炎症中，SEMA7局部表达升高，对其敲除可以恢复TGFβ信号从而减轻炎症程度。

Dec 25, 2024 · SEMA7A (Semaphorin 7A (JohnMiltonHagen Blood Group)) is a Protein Coding gene. Diseases associated with SEMA7A include Cholestasis, Progressive Familial Intrahepatic, 11 and Blood Group, John Milton Hagen System .

Semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) (SEMA7A) also known as CD108 (Cluster of Differentiation 108), is a human gene. [5] SEMA7A is a membrane-bound semaphorin that associates with cell surfaces via a glycosylphosphatidylinositol (GPI

Jan 30, 2023 · Semaphorin7a (SEMA7A), a membrane-anchored member of the semaphorin protein family, could be involved in a diverse range of immune responses via its receptor integrin β1.

Aug 10, 2020 · Semaphorin7A (Sema7A) has been reported to regulate nerve and vessel homeostasis, but its role in EndMT remains unclear. Here we investigate the effect of Sema7A on EndMT and the underlying...

在其家族的8个亚群中，SEMA7A是唯一的膜结合型糖基化磷脂酰肌醇（glycosylphosphatidylinostol， GPI）结合蛋白。 SEMA7A多表达于活化的T细胞表面。 目前已知其有2种受体，受体神经丛蛋白C1（plexin C1）表达于DC、单核细胞和中性粒细胞表面，而整合素α1β1（integrin α1β1 ...

Sema7A是迄今为止Sema家族中唯一一个与糖基化磷脂酰肌醇（glycosylphosphatidylinositol，GPI）相偶联的膜相关糖蛋白。 Sema7A主要通过与受体神经丛蛋白C1和整合素α1β1结合而发挥作用。

Jul 24, 2003 · We show here that semaphorin 7A (Sema7A), a membrane-anchored member of the semaphorin family of guidance proteins previously known for its immunomodulatory effects, can also mediate neuronal...

关于 sema7a Cytogenetic location: 15q24.1 Genomic coordinates (GRCh38): 15:74,409,289-74,433,958 (from NCBI) This gene has 4 transcripts (splice variants), 1 gene allele, 202 orthologues, 19 paralogues and is associated with 2 phenotypes.

Feb 8, 2025 · Title: A Comprehensive Prognostic Analysis of Tumor-Related Blood Group Antigens in Pan-Cancers Suggests That SEMA7A as a Novel Biomarker in Kidney Renal Clear Cell Carcinoma. Anoikis resistance in mammary epithelial cells is mediated by semaphorin 7a.