STAT4 - Wikipedia
Signal transducer and activator of transcription 4 (STAT4) is a transcription factor belonging to the STAT protein family, composed of STAT1, STAT2, STAT3, STAT4, STAT5A, STAT5B, …
STAT4: an immunoregulator contributing to diverse human ...
Signal transducer and activator of transcription 4 (STAT4) is a member of the STAT family and localizes to the cytoplasm. STAT4 is phosphorylated after a variety of cytokines bind to the …
STAT4 Gene - GeneCards | STAT4 Protein | STAT4 Antibody
2024年12月25日 · STAT4 (Signal Transducer And Activator Of Transcription 4) is a Protein Coding gene. Diseases associated with STAT4 include Disabling Pansclerotic Morphea Of …
STAT4: Genetics, Mechanisms, and Implications for ...
STAT4 is a transcription factor that transduces interleukin-12, interleukin-23, and type I interferon cytokine signals in T cells and monocytes, leading to T-helper type 1 and T-helper type 17 …
The biology of Stat4 and Stat6 | Oncogene - Nature
2000年5月25日 · In this review, we will focus on two STAT proteins, Stat6 and Stat4, which are activated specifically by IL-4 and IL-12, respectively. Both of these STATs have been found to …
Discrete Roles of STAT4 and STAT6 transcription factors in ...
Signal transducer and activator of transcription 4 (STAT4) and STAT6 are key factors in the specification of helper T cells; however, their direct roles in driving differentiation are not well …
The JAK/STAT signaling pathway: from bench to clinic
2021年11月26日 · STAT4, STAT5, and STAT6 can be used as targets for ubiquitin-dependent destruction, while STAT1, STAT2, and STAT3 are more stable, indicating that the …