
SOX11 - Wikipedia
Transcription factor SOX-11 is a protein that in humans is encoded by the SOX11 gene. [5][6][7] This intronless gene encodes a member of the group C SOX (SRY-related HMG-box) transcription factor family involved in the regulation of embryonic development and in the determination of the cell fate.
SOX11 Gene - GeneCards | SOX11 Protein | SOX11 Antibody
2024年12月25日 · SOX11 (SRY-Box Transcription Factor 11) is a Protein Coding gene. Diseases associated with SOX11 include Intellectual Developmental Disorder With Microcephaly And With Or Without Ocular Malformations Or Hypogonadotropic Hypogonadism and Hypogonadotropic Hypogonadism .
SOX11 expression is highly specific for mantle cell lymphoma and ...
Overexpression of the transcription factor SOX11 has been observed in conventional mantle cell lymphoma. The aim of this study was to determine whether this gene is expressed in cyclin D1-negative mantle cell lymphoma and whether its detection may be useful to identify these tumors.
SOX11 gene - MedlinePlus
The SOX11 gene provides instructions for making a protein that plays a critical role in the development of the brain and nerve cells (neurons). Learn about this gene and related health conditions.
Regulatory roles for SOX11 in development, stem cells and cancer
2020年12月1日 · We review studies that show roles for SOX11 in regulating development of a variety of embryonic tissues and those that indicate SOX11 as a key regulator of progenitor/ stem cells.
Systematic Investigation of the Multifaceted Role of SOX11 in …
SRY-box transcription factor 11 (SOX11), as a member of the SOX family, is a transcription factor involved in the regulation of specific biological processes and has recently been found to be a prognostic marker for certain cancers. However, the roles …
SOX11 regulates SWI/SNF complex components as member of …
2023年3月7日 · In this work, we show that SOX11 acts as a master transcription and dependency factor in adrenergic NB cells. We identify and validate SOX11 target genes which includes genes involved in...
SOX11 SRY-box transcription factor 11 [ (human)] - National …
SOX11 expression is restricted to EBV-negative Burkitt lymphoma and is associated with molecular genetic features. SOX11 is a novel binding partner and endogenous inhibitor of SAMHD1 ara-CTPase activity in mantle cell lymphoma. SOX11/PRDX2 axis modulates redox homeostasis and chemoresistance in aggressive mantle cell lymphoma.
SOX11 is a biomarker for cyclin D1-negative mantle cell lymphoma
SOX11 expression was detected in most cyclin D1- negative MCL and can serve as a specific biomarker for the diagnosis of this subset of MCL. Lack of SOX11 expression in MCL was associated with an indolent subset and favorable prognosis. Mantle cell lymphoma (MCL) is a distinct subtype of non-Hodgkin lymphoma [1].
SOX11: a potentially useful marker in surgical pathology: a …
SOX11 showed prominent expression in neuroectodermal tumours with neural differentiation, high grade-NEC, SDC, rhabdomyosarcoma and MRCL. The high sensitivity and specificity of SOX11 in SDC and MRCL make it a useful diagnostic marker.