SOCS3 is a conserved gene, found in across the animal kingdom, including Drosophila, [7] chickens, [8] and crocodiles. [9] The expression of SOCS3 gene is induced by various …

SOCS3 regulates cytokine or hormone signaling usually preventing, but in some cases aggravating, a variety of diseases. A main role of SOCS3 results from its binding to both the …

2024年12月25日 · SOCS3 (Suppressor Of Cytokine Signaling 3) is a Protein Coding gene. Diseases associated with SOCS3 include Dermatitis, Atopic, 4 and Hematologic Cancer. …

2014年2月19日 · SOCS3 regulates cytokine or hormone signaling usually preventing, but in some cases aggravating, a variety of diseases. A main role of SOCS3 results from its binding to both …

Suppressor of cytokine signaling-3 expression and its regulation in relation to inflammation in Chronic Obstructive Pulmonary Disease. SOCS3, Transcriptionally Activated by NR4A1, …

After 20 years of extensive research, SOCS3 has emerged as arguably the most important family member, through its regulation of both cytokine- and pathogen-induced cascades. In fact, low …

The suppressor of cytokine signalling-3 (SOCS3) is well known as a feedback inhibitor of the Janus kinases-signal transducer and activator of transcription 3 (JAK/STAT3) signalling …

We used various computational tools to explore the expression and pathogenic roles of SOCS3 in several types of cancer, assessing its potential role in the pathogenesis of cancer, in tumor …

2007年5月18日 · Suppressor of cytokine signalling (SOCS) proteins are inhibitors of the Janus kinase–signal transducer and activator of transcription (JAK–STAT) pathways. SOCS1 also …

2020年8月13日 · Specifically, this review describes defects in JAK1, STAT3, and SOCS3 signaling in mouse models and in humans, including mutations designed to modify these …