2019年3月6日 · Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are now believed to be variants of the same condition, distinct from erythema multiforme. SJS/TEN is a rare, acute , serious, and potentially fatal skin reaction in …

SJS-TEN images. Images of Stevens Johnson syndrome / toxic epidermal necrolysis. Authoritative facts from DermNet New Zealand.

2017年2月19日 · Stevens Johnson syndrome /toxic epidermal necrolysis (SJS/TEN) is a very severe and acute skin disease, almost always caused by a drug. SJS/TEN is characterised by an extensive necrosis and detachment of the epidermis, which involves skin and mucosal surfaces (genitals, eyes, and mouth).

Systemic symptoms such as fever and malaise, are absent or mild in EM but are prominent in SJS/TEN, especially in the prodromal period. Fever, when present in EM, is mild ( 38.5 C) compared to high fevers with SJS/TEN. Patients with SJS/TEN are systemically ill. Outcome and prognosis – virtually all patients with EM recover with no sequelae.

It may have overlapping features with Stevens–Johnson syndrome / toxic epidermal necrolysis (SJS/TEN) and acute generalised exanthematous pustulosis (AGEP). Who gets drug hypersensitivity syndrome? Drug hypersensitivity syndrome is relatively rare. It mainly affects adults and is equal in incidence in males and females.

2016年10月3日 · SJS/TEN often presents with a few days of prodromal illness with fever (> 39 C), malaise, cough, a blocked or runny nose, sore throat and sore eyes. The rash then appears and extends over 5–7 days. It usually starts on the face, chest, and …

Triggers for Stevens Johnson syndrome / toxic epidermal necrolysis. Authoritative facts about the skin from DermNet New Zealand.

In Stevens-Johnson syndrome / toxic epidermal necrolysis (SJS/TEN), they are flat (macular). What are targetoid lesions? Targetoid lesions have concentric zones and look similar to target lesions but are not due to erythema multiforme. They may evolve over a different time frame. Several skin conditions cause targetoid lesions. Melanocytic naevus

Erythema is followed by extensive full thickness cutaneous and mucosal necrosis and denudation within 2 or 3 days. Similar symptoms and signs involving less than 10% of the body surface are classified as Stevens-Johnson syndrome (SJS); if 10-30% of body surface area is affected it is classified as T.E.N. / SJS overlap.

Erythema multiforme (EM) is conventionally separated into EM minor and EM major. It is now separated from Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (T.E.N.). Clinical features EM minor. EM is more common in men than women and 50% are under 20 years of age.