2024年12月25日 · SCARB1 (Scavenger Receptor Class B Member 1) is a Protein Coding gene. Diseases associated with SCARB1 include High Density Lipoprotein Cholesterol Level …

2023年8月29日 · Scavenger receptor class B type I, also known as SCARB1 or CLA-1 (CD-36 and LIMPII analog 1), is a membrane protein with a molecular weight of 82 kDa that acts as …

The SR-B1 (SCARB1) gene directs the synthesis of a membrane protein that removes cholesterol from spherical HDL. The RCT hypothesis ( Fig. 1 ), suggests SR-B1 may play an important …

Mechanistically, SCARB1 inhibits ferroptosis through the regulation of cholesterol metabolism, and the upregulation of CoQ10 level is demonstrated to mediate the suppression of ferroptosis …

2016年9月20日 · Human SCARB1 gene variants are associated with a new lipid phenotype, characterized by high levels of both HDL cholesterol and Lp (a). SCARB1 exonic variants …

2008年8月1日 · Studies suggest that the SCARB1 gene may contribute to variation in plasma lipid levels at fasting; however, the results have been inconsistent, and it is unclear whether …

2025年2月8日 · SCARB1 gene variants are associated with a new lipid phenotype, characterized by high levels of both HDL cholesterol and Lp(a). SCARB1 exonic variants often result in …

Using whole exome sequencing, we have identified rare, compound heterozygous variants in SCARB1 that segregate with severe, premature CAD, following patterns of Mendelian …

Scavenger receptor B type 1 (SR-B1) is a cell surface HDL receptor that mediates HDL-CE uptake. It is most abundantly expressed in liver, where it provides cholesterol for bile acid …

2025年1月18日 · SCARB1 enhances ferroptosis resistance through the upregulation of cholesterol metabolism and CoQ10. SCARB1 promotes radioresistance through the …