2022年4月25日 · Alterations of SATB2 gene (including intragenic duplication, deletions and point mutations in 2q32-q33) have been associated with SATB2 associated syndrome (SAS) (Am J Med Genet A 2014;164A:3083) Phenotype is characterized by intellectual disability and craniofacial abnormalities, including cleft palate, dysmorphic features and dental ...

2023年11月3日 · SATB2 in up to 46% of cases, with patchy and weak staining in most cases, strong and diffuse staining in < 10% of cases (Arch Pathol Lab Med 2017;141:1155) MUC1 (EMA): positive in up to 53% of cases (Am J Clin Pathol 2007;128:808) MUC2: positive in up to 57% of cases Villin: positive in up to 67% of cases (can be focal)

2025年3月4日 · Colon / appendix: CDX2 CK20 CMV chromogranin colon cancer biomarker testing (including MSI / Lynch) HER2 colon Ki67 MLH1 MSH1 MSH2 MSH6 PMS2 SATB2 synaptophysin Esophagus: adenovirus CK7 CK20 claudin 18.2 (pending) CMV GMS HER2 stomach GEJ HSV INSM1 MLH1 MSH2 MSH6 p53 p63 PAS PD-L1 (pending) PMS2 …

2023年10月12日 · SATB2, expressed in bone forming lesions, may be expressed in up to 89% of cases (Histopathology 2013;63 ...

2022年6月1日 · Biopsy from a lytic mass located at the proximal part of the right tibia of a 15 year old boy is represented in the above figures. Immunohistochemically, tumor cells showed a dot-like CD99 expression as well as TLE1 and SATB2 coexpression. Desmin and AE1 / AE3 were negative. What is the expected molecular alteration of this tumor? BCOR::CCNB3 ...

Giant cell tumor of bone, NOS (GCTB) is a locally aggressive and rarely metastasizing neoplasm composed of neoplastic mononuclear stromal cells admixed with macrophages and osteoclast-like giant cells

Frequently beta catenin, CD10, SATB2 and CDX2+ but ER and p63- Caveat: some EECs may demonstrate nuclear expression of beta catenin (i.e. positive) due to CTNNB1 mutation Papillary syncytial metaplasia / eosinophilic syncytial change: Can have variable cellular atypia

2025年1月16日 · SATB2. Negative stains. CK7, except in rectal adenocarcinomas (Appl Immunohistochem Mol Morphol 2009;17: ...

2021年9月28日 · A. CK7, CK20, CDX2, SATB2 and PAX8. Low grade appendiceal mucinous neoplasm is usually positive for CK20, CDX2 and SATB2 and negative for CK7 and PAX8. Comment Here Reference: Mucinous cystadenoma / adenofibroma

Lower gastrointestinal: CDX2, CK20 and SATB2 Hepatocellular carcinoma: Arginase1, HepPar1, Glypican 3 Renal cell carcinoma: PAX8, CAIX, RCC, CD10 Prostate: NKX 3.1, PSA Squamous cell carcinoma: p40 and p63, CK5/6 (also positive in mesothelial cells) Neuroendocrine neoplasm: synaptophysin, chromogranin, INSM1, CD56