Mar 20, 2023 · Ribonuclease inhibitor 1, also known as angiogenin inhibitor 1, encoded by RNH1, is a ubiquitously expressed leucine-rich repeat protein, which is highly conserved in …

Dec 25, 2024 · RNH1 (Ribonuclease/Angiogenin Inhibitor 1) is a Protein Coding gene. Diseases associated with RNH1 include Encephalitis, Acute, Infection-Induced 12 and Lung Cancer.

RNH1 binds to ribosomes and regulates erythropoiesis by controlling translation of the erythroid transcription factor GATA1. Results show that a low expression of RNH1 in metastasis of …

Ribonuclease inhibitor is an enzyme that in humans is encoded by the RNH1 gene. [5]

Jan 28, 2021 · RNH1, which intimately interacts with ANG to inhibit its ribonucleolytic activity, can also bind to the 40S ribosomes and control translation by yet to be known mechanisms. Here, …

RNH1, which intimately interacts with ANG to inhibit its ribonucleolytic activity, can also bind to the 40S ribosomes and control translation by yet to be known mechanisms. Here, we review …

May 31, 2024 · RNH1-mediated cell type–specific translation is mechanistically linked to angiogenin-induced ribosomal biogenesis. Collectively, this study unravels the existence of …

Mar 20, 2023 · Ribonuclease inhibitor 1, also known as angiogenin inhibitor 1, encoded by RNH1, is a ubiquitously expressed leucine-rich repeat protein, which is highly conserved in …

Nov 5, 2024 · Ribonuclease Inhibitor (RNH1), conventionally known for it's role in inhibiting pancreatic ribonucleases, has emerged as a regulator of hematopoiesis, with pivotal functions …

Apr 21, 2023 · Loss-of-function mutations in the human RNH1 gene affects brain, muscles, eyes and cause infection-induced psychomotor deterioration, seizures, and macrocytic anemia. …

Ribonuclease inhibitor 1, also known as angiogenin inhibitor 1, encoded by RNH1, is a ubiquitously expressed leucine-rich repeat protein, which is highly conserved in mammalian …

Human and mouse molecular genetics have uncovered important physiological functions of Ribonuclease inhibitor 1 (RNH1). Constitutive Rnh1 knockout in mice is embryonically lethal, …

Nov 11, 2016 · Ribonuclease inhibitor (RNH1) is a cytosolic protein that binds with femtomolar affinity to human ribonuclease 1 (RNase 1) and homologous secretory ribonucleases. RNH1 …

Nov 15, 2022 · RNH1 is known for its strong interaction with angiogenin (ANG) to inhibit its ribonucleolytic activity. Previously, we have detected RNH1 in polysome fractions and shown …

Our study investigates RNH1 dynamics in sepsis, its links to mortality and organ dysfunction, and the interplay with RNase 1 and RNase 5. Furthermore, we explore RNH1 as a therapeutic …

Dec 6, 2014 · Ribonuclease Inhibitor (RNH1) is a ubiquitously expressed leucine-rich repeat protein. The human RNH1 gene evolved via gene duplication and is conserved among …

Nov 5, 2024 · Ribonuclease Inhibitor (RNH1), conventionally known for it's role in inhibiting pancreatic ribonucleases, has emerged as a regulator of hematopoiesis, with pivotal functions …

Nov 13, 2019 · Recently, we have published that Ribonuclease inhibitor (RNH1) regulates erythropoiesis by controlling GATA1 mRNA translation. Here, we report that RNH1, which is …

Nov 15, 2022 · Previously, we have published that Ribonuclease inhibitor (RNH1) deletion in mice leads to defect inembryonic erythropoiesis. Here, we report that RNH1 regulates myeloid …