Common terms & patterns - Pathology Outlines
2023年1月30日 · Elongated rete ridges usually extend into dermis Can be regular (all rete pegs at roughly the same level) or irregular (rete pegs at different levels of the papillary dermis) Anagen: Hair during growth phase Anaplasia: Atypical nuclei (abnormal in size and shape) and pleomorphism (variation in nuclear characteristics) Asteroid body:
Pathology Outlines - Verruca vulgaris
2023年6月2日 · Inward cupping of the rete pegs is not apparent Proliferative verrucous leukoplakia: May be confused with verruca vulgaris on small, incisional biopsies Patients with verrucous leukoplakia often demonstrate multiple, flattened or slightly raised, well demarcated white plaques Often affects marginal gingiva
Pathology Outlines - Verrucous carcinoma
2023年6月8日 · Comment: Microscopic examination reveals atypical superficial stratified squamous epithelium overlying fibrous connective tissue. The epithelium exhibits a significantly thickened layer of orthokeratin that forms prominent church spire-like peaks. The rete ridges are bulbous and elongated, forming a broad, pushing margin that abuts skeletal muscle.
Pathology Outlines - Anatomy, histology & grossing
2013年10月1日 · Inner two thirds has very thin epidermis which lacks rete pegs, no / reduced number of ceruminous glands and dermal adnexa; contains bone not cartilage Cerumen: watery fluid devoid of lipids; drains from glands into ducts which open into hair sacs of ear canal hairs; fluid mixes with sebaceous gland secretions to produce cerumen (wax)
Pathology Outlines - HPV associated SIL
2021年1月6日 · High grade squamous intraepithelial lesion Acanthosis, papillomatosis, enlarged atypical nuclei in all cell layers including middle and upper third of the epithelium (full thickness atypia), suprabasal mitoses, atypical mitosis, extension in hair follicles and skin appendages (Pathology 2013;45:214)
Conjunctival melanocytic intraepithelial lesions (CMIL)
2024年4月4日 · See also benign melanosis; 11% of conjunctival melanocytic proliferations (Arch Pathol Lab Med 2010;134:1785)
Pathology Outlines - Seborrheic keratosis
2022年5月17日 · Lentigo has pigmented, nonanastomotic, bulbous rete and no horn cysts Malignant melanoma: Malignant melanocytes with invasion into the dermis Pigmented basal cell carcinoma: Clefting, peripheral palisading, mucin, apoptosis and mitosis Condyloma acuminatum: Koilocytes Dysplastic changes
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2021年11月9日 · Regular acanthosis, often with elongated rete (psoriasiform) Alternating zones of hypo and hypergranulosis in the epidermis Thinning of the suprapapillary plates Areas of parakeratosis in the stratum corneum with mounds of neutrophils (Munro microabscesses)
Pathology Outlines - Leukoplakia
2021年2月15日 · Elongated rete ridges, occasionally confluent at tips No epithelial atypia Fibrosis and sparse chronic inflammation Chronic frictional / factitial keratosis: Shaggy / macerated parakeratosis with superficial bacterial colonization Epithelial hyperplasia with keratinocyte edema but no epithelial atypia
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