Reninomas are benign tumors originating from the cells of the juxtaglomerular apparatus. They produce excessive amounts of renin, leading to secondary hyperaldosteronism. As a consequence of this hormonal activation, patients develop severe hypertension, potassium wasting, and hypokalemia.

Reninoma, a renin-secreting juxtaglomerular cell tumor, is a rare cause of severe hypertension that is usually diagnosed in adolescents and young adults. Surgical resection of the tumor completely cures the hypertension of patients with reninoma.

2023年8月30日 · A reninoma is a functional tumor of afferent arteriolar juxtaglomerular cells that secretes the enzyme renin, leading to hyperactivation of the renin-angiotensin-aldosterone system. Reninoma is a potentially curable cause of pathological secondary hyperaldosteronism that results in often severe hypertension and hypokalemia.

A reninoma is a functional tumor of afferent arteriolar juxtaglomerular cells that secretes the enzyme renin, leading to hyperactivation of the renin-angiotensin-aldosterone system. Reninoma is a potentially curable cause of pathological secondary ...

Juxtaglomerular cell tumor (JCT, JGCT, also reninoma) is an extremely rare kidney tumour of the juxtaglomerular cells, with fewer than 100 cases reported in literature. This tumor typically secretes renin, hence the former name of reninoma.

2016年4月18日 · A reninoma is a rare tumor, first described by Robertson et al in 1967, 1 that originates in juxtaglomerular cells and produces excessive renin.

Reninoma, a renin-secreting juxtaglomerular cell tumor, is a rare cause of severe hypertension that is usually diagnosed in adolescents and young adults. Surgical resection of the tumor completely cures the hypertension of patients with reninoma.

When plasma renin activity (PRA) is high in the absence of renal artery stenosis (RAS), a renin-secreting tumour (RST) (Reninoma) should be considered and carefully looked for in imaging. Our patient was found to have this rare tumour, which on surgical resection resulted in a complete cure of hypertension.

2024年1月18日 · Reninoma is a potentially curable cause of pathological secondary hyperaldosteronism that results in often severe hypertension and hypokalemia. The lack of suppression of plasma renin contrasts sharply with the much more common primary aldosteronism, but diagnosis is often prompted by screening for that condition.

2013年5月15日 · When plasma renin activity (PRA) is high in the absence of renal artery stenosis (RAS), a renin-secreting tumour (RST) (Reninoma) should be considered and carefully looked for in imaging. Our patient was found to have this rare tumour, which on surgical resection resulted in a complete cure of hypertension.