c-Raf - Wikipedia
RAF proto-oncogene serine/threonine-protein kinase, also known as proto-oncogene c-RAF or simply c-Raf or even Raf-1, is an enzyme [4] that in humans is encoded by the RAF1 gene. [5] …
RAF1 Gene - GeneCards | RAF1 Protein | RAF1 Antibody
Dec 25, 2024 · RAF1 (Raf-1 Proto-Oncogene, Serine/Threonine Kinase) is a Protein Coding gene. Diseases associated with RAF1 include Leopard Syndrome 2 and Noonan Syndrome 5. …
Raf-1 原癌基因，丝氨酸/苏氨酸激酶（RAF1）基因 | MCE
一旦被激活，细胞 RAF1 蛋白可以磷酸化以激活双重特异性蛋白激酶 MEK1 和 MEK2，后者又磷酸化以激活丝氨酸/苏氨酸特异性蛋白激酶 ERK1 和 ERK2。 激活的 ERK 是细胞生理学的多效 …
RAF kinase - Wikipedia
RAF kinases are a family of three serine/threonine-specific protein kinases that are related to retroviral oncogenes. [11] . The mouse sarcoma virus 3611 contains a RAF kinase-related …
RAF1- 信号通路|蛋白抗体-华美生物
RAF1，即丝裂原活化蛋白激酶激酶1，别名CRAF、Raf-1、Raf激酶等。 它是一种由RAF1基因编码的蛋白激酶，属于RAF家族成员，在多种细胞类型中表达。 RAF1的作用机制涉及作为丝裂 …
【Cell子刊】蛋白质RAF1的结构揭示：抗肺癌新药开发的关键步骤
Sep 2, 2022 · 除了开发对抗KRAS的药物外，目前该领域最活跃的研究之一是寻求识别蛋白质的抑制剂，如RAF1，其负责传递KRAS致癌信号的蛋白质。 2020年，CNIO团队使用了一种小鼠 …
RAF1 gene - MedlinePlus
The RAF1 gene mutations change single protein building blocks (amino acids) in the RAF1 protein. These changes increase protein activity and disrupt the regulation of the RAS/MAPK …
Targeting CRAF kinase in anti-cancer therapy: progress and ...
Dec 18, 2023 · CRAF (RAF1), a member of the RAF kinase family, is an effector of RAS signaling that was first discovered in 1988. CRAF contributes to RAS signaling and exhibits an array of …
Raf-1 原癌基因， 丝氨酸/苏氨酸激酶（Raf1）基因 | MCE
与人 RAF1 同源（Raf-1 原癌基因，丝氨酸/苏氨酸激酶）。 [由基因组资源联盟提供，2022 年 4 月] Enables several functions, including ATP binding activity; Adenylate Cyclase Activator …
RAF1 癌基因 - 癌症123
RAF原癌基因丝氨酸/苏氨酸 - 蛋白激酶，也称为原癌基因c-RAF或简称c-Raf或甚至Raf-1，是一种酶，在人类中由RAF1基因编码。 c-Raf蛋白是ERK1 / 2途径的一部分，作为MAP激酶激酶激 …