Radial glial cells, or radial glial progenitor cells (RGPs), are bipolar-shaped progenitor cells that are responsible for producing all of the neurons in the cerebral cortex. RGPs also produce certain lineages of glia, including astrocytes and oligodendrocytes.

放射状胶质细胞（Radial Glia）是指该细胞在神经发生的早期即自神经上皮细胞衍生在小脑中，此种细胞称为伯格曼细胞（Bergmann's cells），可调控突触可塑性。

Rakic等人的研究揭示了大脑皮层发育起始于胚胎神经系统的脑室区（ventricular zone，vz）的神经上皮细胞（neuroepithelial cells，也称为神经上皮祖细胞progenitor cells，NE或NPC）。 细胞分化的过程一般是干细胞（stem cell）不对称分裂出干细胞和祖细胞，干细胞继续维持干细胞库，祖细胞分化成成熟细胞（mature cell）。 NPC通过对称分裂形成了最初的祖细胞库，然后再转化为 放射状胶质细胞 （radial glia cells，RG或RGC）。 RG不对称分裂出一个突出神经细 …

2005年10月1日 · With the onset of neurogenesis, neuroepithelial cells transform into radial glial cells. Both neuroepithelial and radial glial cells are characterized by apical–basal polarity and...

Radial glial cells originate from the early neural tube neuroepithelial cells (NECs) by a transition that involves acquiring astroglia characteristics. NECs are known for their apico-basal polarity and interkinetic nuclear migration associated with their cell cycle progression.

2005年5月5日 · Radial glial cells have been identified as a major source of neurons during development. Here, we review the evidence for the distinct “glial” nature of radial glial cells and contrast these cells with their progenitors, the neuroepithelial cells.

Radial glial cells (RGCs) are a morphologically, biochemically, and functionally distinct nonneuronal cell class that, during development, radially spans the entire width of the developing cerebral wall from the ventricular cavity to the pial surface. They play several pivotal roles in the production and placement of neurons during vertebrate ...

2014年1月1日 · Today, radial glial cells are recognised as morphologically, biochemically and functionally distinct from other neural cell types. They display an apical–basal polarity possessing a periventricular cell body and an elongated process extending from a ventricular attachment to an end-foot anchored to the opposing pial surface (Fig. 1 A and B ...

Radial glial cells (RGCs) comprise a pseudostratified epithelial layer lining the ventricular wall during cerebral cortex development. RGCs performs asymmetric neurogenic cell division to produce postmitotic neurons or neuronally committed intermediate progenitor cells.

2022年11月15日 · Similar markers have identified radial glia-like cells in the nervous system of non-vertebrate organisms. In this review, we focus on adult radial glia-like cells in neurogenic processes during homeostasis and in response to injury.