The multiple roles of Rab9 in the endolysosomal system - PMC
The small GTPase Rab9 has long been described as a protein that mediates endosome-to-trans-Golgi Network (TGN) transport, and specifically mannose-6-phospate receptor (MPR) …
Rab9 functions in transport between late endosomes and the …
We report here the primary sequence, subcellular localization and functional activity of a new member of the rab protein family, rab9. The majority of rab9 appears to be located on the …
Rab9 functions in transport between late endosomes and the …
We report here the primary sequence, subcellular localization and functional activity of a new member of the rab protein family, rab9. The majority of rab9 appears to be located on the …
Golgi-associated Rab GTPases implicated in autophagy
2021年2月8日 · Rab9. Rab9 GTPase (23 kDa) localized in the late endosome plays an important role in vesicle transport from the late endosome to the trans-Golgi network (TGN) . Rab9 …
RAB9A Gene - GeneCards | RAB9A Protein | RAB9A Antibody
2024年12月25日 · RAB9A (RAB9A, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB9A include Warburg Micro Syndrome 1 and Hermansky-Pudlak …
The multiple roles of Rab9 in the endolysosomal system
2016年7月22日 · More so, the Rab9 constitutively active mutant, Rab9Q66L, accumulates on late endosomes and promotes carrier formation at the TGN. Here, we discuss our findings in light …
Rab9 GTPase Regulates Late Endosome Size and Requires Effector ...
Rab9 GTPase resides in a late endosome microdomain together with mannose 6-phosphate receptors (MPRs) and the tail-interacting protein of 47 kDa (TIP47). To explore the importance …
An alternative mitophagy pathway mediated by Rab9 protects the …
2019年2月1日 · Knockin of Rab9 (S179A) abolished mitophagy and exacerbated the injury in response to myocardial ischemia, without affecting conventional autophagy. Mitophagy …
Rab9 and retromer regulate retrograde trafficking of luminal …
2013年1月15日 · Here we show that an endosomal-retrieval machinery consisting of Rab9, retromer and actin nucleator WASH (Wiskott–Aldrich Syndrome Protein and SCAR Homolog) …
CDD Conserved Protein Domain Family: Rab9 - National Center …
2020年10月2日 · Rab9 is a key mediator of vesicular transport from late endosomes to the trans-Golgi network (TGN) by redirecting the MPRs. Rab9 has been identified as a key component …