Sep 7, 2006 · RNase II is a ubiquitous exoribonuclease that processively hydrolyses RNA in the 3′ to 5′ direction, releasing 5′ monophosphates 1. The enzyme binds RNA and in the presence of …

Jul 5, 2006 · We propose a reaction mechanism for exonucleolytic RNA degradation involving key conserved residues. Our three-dimensional model corroborates all existing biochemical data …

Dec 25, 2024 · RNASE2 (Ribonuclease A Family Member 2) is a Protein Coding gene. Diseases associated with RNASE2 include Pulmonary Eosinophilia and Esophagitis. Among its related …

RNase II is a ubiquitous enzyme that degrades single-stranded RNAs processively in the 3′-to5′-direction, resulting in the generation of 5′-mononucleotides. Ten nucleotides is the minimum …

RNase II is the most active exoribonuclease in Escherichia coli cell extracts. Yet, its removal appears to have no deleterious effect on growing cells. Here, we show that RNase II is …

One of these, RNase II, a monomer with a molecular mass of 72.5 kDa, is hydrolytic and accounts for up to 90% of the exoribonucleolytic activity in crude extracts . The other, polynucleotide …

Feb 14, 2020 · Enzymatic analysis revealed that Alr1240 is an exoribonuclease II (RNase II), as it only degrades non-structured single-stranded RNA substrates. In contrast to known RNase E …

Sep 1, 2006 · In a recent issue of Nature, Frazão et al. 1 report the X-ray crystallographic structure of the 3′→5′ exoribonuclease RNase II from E. coli. 3′ exoribonucleases act on many …

Here we review recent progresses in the understanding of the degradation mechanism of RNase II, based on mutational analysis and their characterization regarding catalysis and RNA affinity.

Apr 17, 2020 · Enzymatic analysis revealed that Alr1240 is an exoribonuclease II (RNase II), as it only degrades non-structured single-stranded RNA substrates. In contrast to known RNase E …