RIG-I-like receptor - Wikipedia
RIG-I-like receptors (retinoic acid-inducible gene-I-like receptors, RLRs) are a type of intracellular pattern recognition receptor involved in the recognition of viruses by the innate immune …
RIG-I-like receptors: their regulation and roles in RNA sensing
2020年3月13日 · Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) are key sensors of virus infection, mediating the transcriptional induction of type I interferons and...
固有免疫（二）：特征识别受体 - 知乎 - 知乎专栏
识别胞质内RNA的蛋白家族叫做RIG-I-like receptor (RLR)。RLR在结构上拥有保守的DExH motif（在helicase domain中)，因此属于DEAD-box家族蛋白（这类蛋白含有保守的DEAD氨 …
天然免疫系统中的模式识别受体 - 知乎 - 知乎专栏
一般认为，PRR包括四类： Toll-like receptors (TLRs)、retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs)、nucleotide oligomerization domain (NOD)-like receptors (NLRs)、C-type …
Physiological functions of RIG-I-like receptors - Cell Press
2024年4月9日 · RIG-I-like receptors (RLRs) are crucial for pathogen detection and triggering immune responses and have immense physiological importance. In this review, we first …
细胞固有天然免疫信号转导 | Cell Signaling Technology
RIG-1 和 MDA5 等 RIG-I 样受体 (RLR) 能检测双链病毒 RNA 和 5'-三磷酸短 dsRNA。MDA5 和 RIG-1 会与共有的 caspase 募集结构域相互作用，从而诱导线粒体抗病毒信号转导蛋白 …
RIG-I-like receptors: their regulation and roles in RNA sensing
Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) are key sensors of virus infection, mediating the transcriptional induction of type I interferons and other genes that collectively …
Regulation of RIG-I-like receptor-mediated signaling: interaction ...
2021年1月18日 · Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) are RNA sensor molecules that play essential roles in innate antiviral immunity.
RIG-Ⅰ样受体介导的RNA识别及其功能机制-SciEngine
视黄酸诱导基因Ⅰ样受体(RIG-Ⅰ like receptor，RLR)是感知宿主胞质内病毒RNA的主要受体。 一方面，RLR识别病毒来源的RNA并引发下游信号通路激活，产生Ⅰ型干扰素，抵抗病毒感染； …
RIG-I-like receptors: their regulation and roles in RNA sensing
Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) are key sensors of virus infection, mediating the transcriptional induction of type I interferons and other genes that collectively …