
RBX1 Gene - GeneCards | RBX1 Protein | RBX1 Antibody
Dec 25, 2024 · RBX1 (Ring-Box 1) is a Protein Coding gene. Diseases associated with RBX1 include Invasive Bladder Transitional Cell Carcinoma and Smith-Magenis Syndrome. Among …
The Cullin3-Rbx1-KLHL9 E3 ubiquitin ligase complex ubiquitinates …
Jan 28, 2025 · We report that the CUL3-RBX1-KLHL9 E3 ubiquitin ligase complex is translocated to the lysosome and ubiquitinates Rheb in response to amino acid stimulation. KLHL9 serves …
RBX1 (RING Box Protein 1) E3 Ubiquitin Ligase Is Required for …
RBX1 (RING box protein 1), also known as ROC1 (Regulator of Cullin 1), is an essential component of SCF (Skp1/Cullins/F-box) E3 ubiquitin ligases, which target diverse proteins for …
RBX1 and RBX2: The RING Components of SCF E3 Ubiquitin Ligases
Sep 8, 2010 · RBX1 and RBX2 are evolutionarily conserved from yeast to humans and play an essential role during mouse embryonic development. Moreover, RBX1 and RBX2 are both …
9978 - Gene ResultRBX1 ring-box 1 [ (human)] - National Center …
RING box protein-1 (RBX1), a key component of SCF E3 ligase, induced multiple myeloma cell drug-resistance though suppressing p27. E3 ubiquitin ligase RBX1 drives the metastasis of …
RBX1/ROC1-SCF E3 ubiquitin ligase is required for mouse ... - PubMed
Aug 6, 2009 · RBX1 (also known as ROC1) is a RING subunit of SCF (Skp1, Cullins, F-box proteins) E3 ubiquitin ligases, required for SCF to direct a timely degradation of diverse …
RBX1/ROC1-SCF E3 ubiquitin ligase is required for mouse …
Aug 6, 2009 · RBX1 (also known as ROC1) is a RING subunit of SCF (S kp1, C ullins, F -box proteins) E3 ubiquitin ligases, required for SCF to direct a timely degradation of diverse …
RBX1 ring-box 1 [Homo sapiens (human)] - Gene - NCBI
Jan 5, 2025 · Title: RING box protein-1(RBX1), a key component of SCF E3 ligase, induced multiple myeloma cell drug-resistance though suppressing p27. E3 ubiquitin ligase RBX1 …
RBX1 prompts degradation of EXO1 to limit the homologous
Sep 27, 2019 · Exonuclease 1 (EXO1) is the key molecule responsible for 3′ ssDNA formation of DSB end resection. We revealed that EXO1 is inactivated in G1-phase cells via ubiquitination …
UniProt
Aug 16, 2004 · Core component of a Cul9-RING ubiquitin ligase complex composed of CUL9 and RBX1, which mediates mono-ubiquitination of p53/TP53 (PubMed:38605244). Recruits the E2 …
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